Bile acid indices as biomarkers for liver diseases I: Diagnostic markers

Figure 1 Receiver operating characteristics curves of bile acids concentrations and indices with area under the receiver operating characteristics curve > 0. 7. The area under the receiver operating characteristics curve (AUC) for differentiating patients from healthy controls. The scale of both the Y-axis (sensitivity) and the X-axis (1-specificity) is 0-1. Bile acids (BA) indices are higher in patients vs. controls, and the positive actual state was patients except the ones annotated with “*”, where BA indices were lower in patients compared to controls. For these BA indices, “1-AUC” instead of “AUC” was calculated. AUC: Area under the receiver operating characteristics curve; BA: Bile acids; CDCA: Chenodeoxycholic acid; CA: Cholic acid; DCA: Deoxycholic acid; HDCA: Hyodeoxycholic acid; MDCA: Murideoxycholic acid; G: Glycine.