Liver dysfunction as a cytokine storm manifestation and prognostic factor for severe COVID-19

Figure 1 Liver dysfunction defined by the negative effects of cytokine storm (severe inflammation, thrombosis, hypoxia, etc. ) during coronavirus disease 2019 infection. Other contributing factors for liver injury are also presented – preexisting liver condition, direct cytopathic action of severe acute respiratory coronavirus 2 and treatment with hepatotoxic drugs.