Opinion Review
Copyright ©The Author(s) 2019.
World J Hepatol. May 27, 2019; 11(5): 412-420
Published online May 27, 2019. doi: 10.4254/wjh.v11.i5.412
Figure 1
Figure 1 Hepatic stellate cell activation and inflammation participate in acute liver failure. A: At homeostasis; B: During acute liver failure, the roles of hepatic stellate cell activation and inflammation remain unclear.
Figure 2
Figure 2 Roles of hepatic stellate cells in liver failure. A: Hepatic stellate cells protect hepatocytes by participating in the maintenance of cell attachment and the architecture of liver tissue via extracellular matrix production; B: Hepatic stellate cells assist liver regeneration by producing growth factors; C: Hepatic stellate cells play a role in relaying inflammation signaling from sinusoids to parenchyma via the secretion of inflammatory cytokines.