Jin-Jun Chen, MD and Prof of internal medicine, deputy director of hepatology unit and Zengcheng Branch of Nanfang Hospital. As a senior clinical doctor and current a physician scientist, several clinical scenarios centered liver cirrhosis, including acute-on chronic liver failure, portal hypertension and decompensation are the focus of my clinical and basic researches. Liver cirrhosis and its related outcomes are the final burdens for patients with chronic liver diseases, which deserve many inputs and efforts from clinical and scientific communities. My team have established several impressive and prospective cohorts derive from liver cirrhosis patients and had hands of academic publications. My team prospectively validated that spleen stiffness measurement via VCTE could avoid endoscopic screening in liver cirrhosis patients, which endorsed Baveno VII recommendations. The second contribution to hepatology community was that cytomegalovirus, a latent infection in general adult population could reactivated in decompensated liver cirrhosis, which would lead to worsen outcomes. Over 20 original research papers as (co) first or (co) corresponding author had been peer reviewed and published in academic journals. H index is over 30 and actively involved in several international associations including APASL and EASL. I have been active in peer reviewing research or review manuscripts for several journals including CGH, AJG, et al. liver cirrhosis, portal hypertension and acute-on chronic liver failure is my focus in clinical work and basic and clinical research. leadership, mentoring and problem-solving in my career. Gym