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Karimov M, Scherer M, Franke H, Ewe A, Aigner A. Analysis of polymeric nanoparticle properties for siRNA/DNA delivery in a tumor xenograft tissue slice air-liquid interface model. Biotechnol J 2022;:e2200415. [PMID: 36541426 DOI: 10.1002/biot.202200415] [Reference Citation Analysis]
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Kubczak M, Michlewska S, Karimov M, Ewe A, Aigner A, Bryszewska M, Ionov M. Comparison of tyrosine-modified low molecular weight branched and linear polyethylenimines for siRNA delivery. Nanotoxicology 2022;16:867-82. [PMID: 36697400 DOI: 10.1080/17435390.2022.2159891] [Reference Citation Analysis]
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Kubczak M, Michlewska S, Karimov M, Ewe A, Noske S, Aigner A, Bryszewska M, Ionov M. Unmodified and tyrosine-modified polyethylenimines as potential carriers for siRNA: Biophysical characterization and toxicity. Int J Pharm 2022;614:121468. [PMID: 35031413 DOI: 10.1016/j.ijpharm.2022.121468] [Reference Citation Analysis]
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Noske S, Karimov M, Hansen M, Zatula N, Ewe A, Aigner A. Non-viral siRNA transfection of primary mesenchymal stromal cells (MSCs): Assessment of tyrosine-modified PEI and PPI efficacy and biocompatibility. Int J Pharm 2022;612:121359. [PMID: 34896217 DOI: 10.1016/j.ijpharm.2021.121359] [Reference Citation Analysis]
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Gong G, Tang X, Zhang J, Liang X, Yang J, Li Q. Phenylboronic Acid-Modified Polyamidoamine Mediated the Transfection of Polo-Like Kinase-1 siRNA to Achieve an Anti-Tumor Efficacy. Int J Nanomedicine 2021;16:8037-48. [PMID: 34934312 DOI: 10.2147/IJN.S329433] [Reference Citation Analysis]
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Karimov M, Schulz M, Kahl T, Noske S, Kubczak M, Gockel I, Thieme R, Büch T, Reinert A, Ionov M, Bryszewska M, Franke H, Krügel U, Ewe A, Aigner A. Tyrosine-modified linear PEIs for highly efficacious and biocompatible siRNA delivery in vitro and in vivo. Nanomedicine 2021;36:102403. [PMID: 33932594 DOI: 10.1016/j.nano.2021.102403] [Cited by in Crossref: 7] [Cited by in F6Publishing: 6] [Article Influence: 3.5] [Reference Citation Analysis]
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Liu X, Chen L, Zhang Y, Xin X, Qi L, Jin M, Guan Y, Gao Z, Huang W. Enhancing anti-melanoma outcomes in mice using novel chitooligosaccharide nanoparticles loaded with therapeutic survivin-targeted siRNA. European Journal of Pharmaceutical Sciences 2021;158:105641. [DOI: 10.1016/j.ejps.2020.105641] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
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Karimov M, Appelhans D, Ewe A, Aigner A. The combined disulfide cross-linking and tyrosine-modification of very low molecular weight linear PEI synergistically enhances transfection efficacies and improves biocompatibility. Eur J Pharm Biopharm 2021;161:56-65. [PMID: 33582186 DOI: 10.1016/j.ejpb.2021.02.005] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
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Fischer D, Dusek N, Hotzel K, Heinze T. The Role of Formamidine Groups in Dextran Based Nonviral Vectors for Gene Delivery on Their Physicochemical and Biological Characteristics. Macromol Biosci 2021;21:e2000220. [PMID: 33025658 DOI: 10.1002/mabi.202000220] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
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Noske S, Karimov M, Aigner A, Ewe A. Tyrosine-Modification of Polypropylenimine (PPI) and Polyethylenimine (PEI) Strongly Improves Efficacy of siRNA-Mediated Gene Knockdown. Nanomaterials (Basel) 2020;10:E1809. [PMID: 32927826 DOI: 10.3390/nano10091809] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 2.0] [Reference Citation Analysis]
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Müller S, Wedler A, Breuer J, Glaß M, Bley N, Lederer M, Haase J, Misiak C, Fuchs T, Ottmann A, Schmachtel T, Shalamova L, Ewe A, Aigner A, Rossbach O, Hüttelmaier S. Synthetic circular miR-21 RNA decoys enhance tumor suppressor expression and impair tumor growth in mice. NAR Cancer 2020;2:zcaa014. [PMID: 34316687 DOI: 10.1093/narcan/zcaa014] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 1.7] [Reference Citation Analysis]
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