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For: Zheng X, Vittar NB, Gai X, Fernandez-Barrena MG, Moser CD, Hu C, Almada LL, McCleary-Wheeler AL, Elsawa SF, Vrabel AM. The transcription factor GLI1 mediates TGFβ1 driven EMT in hepatocellular carcinoma via a SNAI1-dependent mechanism. PLoS One. 2012;7:e49581. [PMID: 23185371 DOI: 10.1371/journal.pone.0049581] [Cited by in Crossref: 50] [Cited by in F6Publishing: 47] [Article Influence: 5.0] [Reference Citation Analysis]
Number Citing Articles
1 Ji Q, Hou J, Yong X, Gong G, Muddassir M, Tang T, Xie J, Fan W, Chen X. Targeted Dual Small Interfering Ribonucleic Acid Delivery via Non-Viral Polymeric Vectors for Pulmonary Fibrosis Therapy. Adv Mater 2021;33:e2007798. [PMID: 33604928 DOI: 10.1002/adma.202007798] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 5.0] [Reference Citation Analysis]
2 Li Q, Liu Z, Xu M, Xue Y, Yao B, Dou C, Jia Y, Wang Y, Tu K, Zheng X, Yao Y. PCAF inhibits hepatocellular carcinoma metastasis by inhibition of epithelial-mesenchymal transition by targeting Gli-1. Cancer Lett 2016;375:190-8. [PMID: 26945969 DOI: 10.1016/j.canlet.2016.02.053] [Cited by in Crossref: 26] [Cited by in F6Publishing: 25] [Article Influence: 4.3] [Reference Citation Analysis]
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8 Peng Y, Li Y, Tian Y, Ao G. PDE4a predicts poor prognosis and promotes metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma. J Cancer 2018;9:2389-96. [PMID: 30026835 DOI: 10.7150/jca.24079] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.8] [Reference Citation Analysis]
9 Gai X, Lu Z, Tu K, Liang Z, Zheng X. Caveolin-1 is up-regulated by GLI1 and contributes to GLI1-driven EMT in hepatocellular carcinoma. PLoS One 2014;9:e84551. [PMID: 24454730 DOI: 10.1371/journal.pone.0084551] [Cited by in Crossref: 23] [Cited by in F6Publishing: 27] [Article Influence: 2.9] [Reference Citation Analysis]
10 Gai X, Tu K, Li C, Lu Z, Roberts LR, Zheng X. Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma. Cell Death Dis 2015;6:e1712. [PMID: 25855960 DOI: 10.1038/cddis.2015.76] [Cited by in Crossref: 26] [Cited by in F6Publishing: 30] [Article Influence: 3.7] [Reference Citation Analysis]
11 Matissek SJ, Elsawa SF. GLI3: a mediator of genetic diseases, development and cancer. Cell Commun Signal 2020;18:54. [PMID: 32245491 DOI: 10.1186/s12964-020-00540-x] [Cited by in Crossref: 13] [Cited by in F6Publishing: 13] [Article Influence: 6.5] [Reference Citation Analysis]
12 Jin J, Xu H, Wu R, Niu J, Li S. Aberrant DNA methylation profile of hepatitis B virus infection. J Med Virol 2019;91:81-92. [PMID: 30118556 DOI: 10.1002/jmv.25284] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
13 Liu Q, Sheng W, Dong M, Dong X, Dong Q, Li F. Gli1 promotes transforming growth factor-beta1- and epidermal growth factor-induced epithelial to mesenchymal transition in pancreatic cancer cells. Surgery 2015;158:211-24. [PMID: 25979438 DOI: 10.1016/j.surg.2015.03.016] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 2.6] [Reference Citation Analysis]
14 Gao H, Wang W, Li Q. GANT61 suppresses cell survival, invasion and epithelial-mesenchymal transition through inactivating AKT/mTOR and JAK/STAT3 pathways in anaplastic thyroid carcinoma. Cancer Biol Ther 2022;23:369-77. [PMID: 35491899 DOI: 10.1080/15384047.2022.2051158] [Reference Citation Analysis]
15 Ding S, Chen G, Zhang W, Xing C, Xu X, Xie H, Lu A, Chen K, Guo H, Ren Z. MRC-5 fibroblast-conditioned medium influences multiple pathways regulating invasion, migration, proliferation, and apoptosis in hepatocellular carcinoma. J Transl Med. 2015;13:237. [PMID: 26198300 DOI: 10.1186/s12967-015-0588-8] [Cited by in Crossref: 13] [Cited by in F6Publishing: 14] [Article Influence: 1.9] [Reference Citation Analysis]
16 Harrison W, Cochrane B, Neill G, Philpott M. The oncogenic GLI transcription factors facilitate keratinocyte survival and transformation upon exposure to genotoxic agents. Oncogene 2014;33:2432-40. [PMID: 23792444 DOI: 10.1038/onc.2013.199] [Cited by in Crossref: 14] [Cited by in F6Publishing: 11] [Article Influence: 1.6] [Reference Citation Analysis]
17 Matissek SJ, Karbalivand M, Han W, Boutilier A, Yzar-garcia E, Kehoe LL, Gardner DS, Hage A, Fleck K, Jeffers V, Rajsbaum R, Elsawa SF. A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling. Oncotarget 2022;13:944-59. [DOI: 10.18632/oncotarget.28261] [Reference Citation Analysis]
18 Tu K, Yang W, Li C, Zheng X, Lu Z, Guo C, Yao Y, Liu Q. Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma. Mol Cancer. 2014;13:110. [PMID: 24884509 DOI: 10.1186/1476-4598-13-110] [Cited by in Crossref: 102] [Cited by in F6Publishing: 96] [Article Influence: 12.8] [Reference Citation Analysis]
19 Song T, Wang C, Guo C, Liu Q, Zheng X. Pentraxin 3 overexpression accelerated tumor metastasis and indicated poor prognosis in hepatocellular carcinoma via driving epithelial-mesenchymal transition. J Cancer 2018;9:2650-8. [PMID: 30087705 DOI: 10.7150/jca.25188] [Cited by in Crossref: 16] [Cited by in F6Publishing: 17] [Article Influence: 4.0] [Reference Citation Analysis]
20 Nye MD, Almada LL, Fernandez-Barrena MG, Marks DL, Elsawa SF, Vrabel A, Tolosa EJ, Ellenrieder V, Fernandez-Zapico ME. The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor β-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner. J Biol Chem 2014;289:15495-506. [PMID: 24739390 DOI: 10.1074/jbc.M113.545194] [Cited by in Crossref: 35] [Cited by in F6Publishing: 23] [Article Influence: 4.4] [Reference Citation Analysis]
21 Zheng X, Xu M, Yao B, Wang C, Jia Y, Liu Q. IL-6/STAT3 axis initiated CAFs via up-regulating TIMP-1 which was attenuated by acetylation of STAT3 induced by PCAF in HCC microenvironment. Cell Signal 2016;28:1314-24. [PMID: 27297362 DOI: 10.1016/j.cellsig.2016.06.009] [Cited by in Crossref: 31] [Cited by in F6Publishing: 31] [Article Influence: 5.2] [Reference Citation Analysis]
22 Kim Y, Do IG, Hong M, Suh YL. Negative prognostic effect of low nuclear GLI1 expression in glioblastomas. J Neurooncol 2017;133:69-76. [PMID: 28417299 DOI: 10.1007/s11060-017-2426-8] [Reference Citation Analysis]
23 Wang C, Dou C, Wang Y, Liu Z, Roberts L, Zheng X. TLX3 repressed SNAI1-induced epithelial-mesenchymal transition by directly constraining STAT3 phosphorylation and functionally sensitized 5-FU chemotherapy in hepatocellular carcinoma. Int J Biol Sci 2019;15:1696-711. [PMID: 31360112 DOI: 10.7150/ijbs.33844] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
24 Li H, Da LJ, Fan WD, Long XH, Zhang XQ. Transcription factor glioma-associated oncogene homolog 1 is required for transforming growth factor-β1-induced epithelial-mesenchymal transition of non-small cell lung cancer cells. Mol Med Rep 2015;11:3259-68. [PMID: 25586417 DOI: 10.3892/mmr.2015.3150] [Cited by in Crossref: 5] [Cited by in F6Publishing: 7] [Article Influence: 0.7] [Reference Citation Analysis]
25 Choe C, Shin YS, Kim C, Choi SJ, Lee J, Kim SY, Cho YB, Kim J. Crosstalk with cancer-associated fibroblasts induces resistance of non-small cell lung cancer cells to epidermal growth factor receptor tyrosine kinase inhibition. Onco Targets Ther 2015;8:3665-78. [PMID: 26676152 DOI: 10.2147/OTT.S89659] [Cited by in Crossref: 25] [Cited by in F6Publishing: 24] [Article Influence: 3.6] [Reference Citation Analysis]
26 Shen G, Lin Y, Yang X, Zhang J, Xu Z, Jia H. MicroRNA-26b inhibits epithelial-mesenchymal transition in hepatocellular carcinoma by targeting USP9X. BMC Cancer. 2014;14:393. [PMID: 24890815 DOI: 10.1186/1471-2407-14-393] [Cited by in Crossref: 53] [Cited by in F6Publishing: 51] [Article Influence: 6.6] [Reference Citation Analysis]
27 Yılmaz Y, Güneş A, Topel H, Atabey N. Signaling Pathways as Potential Therapeutic Targets in Hepatocarcinogenesis. J Gastrointest Cancer 2017;48:225-37. [PMID: 28819741 DOI: 10.1007/s12029-017-9958-1] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.4] [Reference Citation Analysis]
28 Xie G, Diehl AM. Evidence for and against epithelial-to-mesenchymal transition in the liver. Am J Physiol Gastrointest Liver Physiol 2013;305:G881-90. [PMID: 24157970 DOI: 10.1152/ajpgi.00289.2013] [Cited by in Crossref: 66] [Cited by in F6Publishing: 65] [Article Influence: 7.3] [Reference Citation Analysis]
29 Xu G, Qi F, Zhang J, Xu J, Shi T, Miao Y. Overexpression of OCT4 contributes to progression of hepatocellular carcinoma. Tumour Biol 2016;37:4649-54. [PMID: 26508029 DOI: 10.1007/s13277-015-4285-2] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 0.7] [Reference Citation Analysis]
30 Carr RM, Romecin Duran PA, Tolosa EJ, Ma C, Oseini AM, Moser CD, Banini BA, Huang J, Asumda F, Dhanasekaran R, Graham RP, Toruner MD, Safgren SL, Almada LL, Wang S, Patnaik MM, Roberts LR, Fernandez-Zapico ME. The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex. J Biol Chem 2020;295:2698-712. [PMID: 31988246 DOI: 10.1074/jbc.RA119.011146] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
31 Gai X, Tu K, Lu Z, Zheng X. MRC2 expression correlates with TGFβ1 and survival in hepatocellular carcinoma. Int J Mol Sci. 2014;15:15011-15025. [PMID: 25162823 DOI: 10.3390/ijms150915011] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 2.1] [Reference Citation Analysis]
32 Xiong D, Liou Y, Shu J, Li D, Zhang L, Chen J. Down-regulating ribonuclease inhibitor enhances metastasis of bladder cancer cells through regulating epithelial-mesenchymal transition and ILK signaling pathway. Exp Mol Pathol 2014;96:411-21. [PMID: 24768914 DOI: 10.1016/j.yexmp.2014.04.012] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 1.1] [Reference Citation Analysis]
33 Zhang D, Cao L, Li Y, Lu H, Yang X, Xue P. Expression of glioma-associated oncogene 2 (Gli 2) is correlated with poor prognosis in patients with hepatocellular carcinoma undergoing hepatectomy. World J Surg Oncol 2013;11:25. [PMID: 23356443 DOI: 10.1186/1477-7819-11-25] [Cited by in Crossref: 24] [Cited by in F6Publishing: 23] [Article Influence: 2.7] [Reference Citation Analysis]
34 Cervello M, Augello G, Cusimano A, Emma MR, Balasus D, Azzolina A, Mccubrey JA, Montalto G. Pivotal roles of glycogen synthase-3 in hepatocellular carcinoma. Advances in Biological Regulation 2017;65:59-76. [DOI: 10.1016/j.jbior.2017.06.002] [Cited by in Crossref: 24] [Cited by in F6Publishing: 25] [Article Influence: 4.8] [Reference Citation Analysis]
35 Cheng J, Gao J, Tao K. Prognostic role of Gli1 expression in solid malignancies: a meta-analysis. Sci Rep 2016;6:22184. [PMID: 26899488 DOI: 10.1038/srep22184] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 2.8] [Reference Citation Analysis]
36 Xu M, Liu Z, Wang C, Yao B, Zheng X. EDG2 enhanced the progression of hepatocellular carcinoma by LPA/PI3K/AKT/ mTOR signaling. Oncotarget 2017;8:66154-68. [PMID: 29029500 DOI: 10.18632/oncotarget.19825] [Cited by in Crossref: 12] [Cited by in F6Publishing: 16] [Article Influence: 2.4] [Reference Citation Analysis]
37 Lin WF, Lin XL, Fu SW, Yang L, Tang CT, Gao YJ, Chen HY, Ge ZZ. Pseudopod-associated protein KIF20B promotes Gli1-induced epithelial-mesenchymal transition modulated by pseudopodial actin dynamic in human colorectal cancer. Mol Carcinog 2018;57:911-25. [PMID: 29573464 DOI: 10.1002/mc.22812] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.0] [Reference Citation Analysis]
38 Nwabo Kamdje AH, Takam Kamga P, Tagne Simo R, Vecchio L, Seke Etet PF, Muller JM, Bassi G, Lukong E, Kumar Goel R, Mbo Amvene J, Krampera M. Developmental pathways associated with cancer metastasis: Notch, Wnt, and Hedgehog. Cancer Biol Med 2017;14:109-20. [PMID: 28607802 DOI: 10.20892/j.issn.2095-3941.2016.0032] [Cited by in Crossref: 43] [Cited by in F6Publishing: 50] [Article Influence: 8.6] [Reference Citation Analysis]
39 Jia YL, Xu M, Dou CW, Liu ZK, Xue YM, Yao BW, Ding LL, Tu KS, Zheng X, Liu QG. P300/CBP-associated factor (PCAF) inhibits the growth of hepatocellular carcinoma by promoting cell autophagy. Cell Death Dis 2016;7:e2400. [PMID: 27711074 DOI: 10.1038/cddis.2016.247] [Cited by in Crossref: 20] [Cited by in F6Publishing: 22] [Article Influence: 3.3] [Reference Citation Analysis]
40 Chai JY, Sugumar V, Alshawsh MA, Wong WF, Arya A, Chong PP, Looi CY. The Role of Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis. Biomedicines 2021;9:1188. [PMID: 34572373 DOI: 10.3390/biomedicines9091188] [Reference Citation Analysis]
41 Tu KS, Yao YM. Epithelial-mesenchymal transition and related signaling pathways in hepatocellular carcinoma. Shijie Huaren Xiaohua Zazhi 2016; 24(14): 2131-2142 [DOI: 10.11569/wcjd.v24.i14.2131] [Reference Citation Analysis]
42 Luo Y, Jin H, Wen GR, Tuo BG. Advances in differentiation therapy of hepatocellular carcinoma. Shijie Huaren Xiaohua Zazhi 2015; 23(29): 4665-4672 [DOI: 10.11569/wcjd.v23.i29.4665] [Reference Citation Analysis]
43 Dou C, Liu Z, Xu M, Jia Y, Wang Y, Li Q, Yang W, Zheng X, Tu K, Liu Q. miR-187-3p inhibits the metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting S100A4. Cancer Lett. 2016;381:380-390. [PMID: 27544906 DOI: 10.1016/j.canlet.2016.08.011] [Cited by in Crossref: 65] [Cited by in F6Publishing: 71] [Article Influence: 10.8] [Reference Citation Analysis]
44 Dou C, Zhou Z, Xu Q, Liu Z, Zeng Y, Wang Y, Li Q, Wang L, Yang W, Liu Q, Tu K. Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca2+/PI3K/AKT pathway. Oncogene. 2019;38:1239-1255. [PMID: 30250300 DOI: 10.1038/s41388-018-0505-8] [Cited by in Crossref: 42] [Cited by in F6Publishing: 51] [Article Influence: 10.5] [Reference Citation Analysis]
45 Xu M, Jia Y, Liu Z, Ding L, Tian R, Gu H, Wang Y, Zhang H, Tu K, Liu Q. Chromatin assembly factor 1, subunit A (P150) facilitates cell proliferation in human hepatocellular carcinoma. Onco Targets Ther 2016;9:4023-35. [PMID: 27445493 DOI: 10.2147/OTT.S107050] [Cited by in Crossref: 8] [Cited by in F6Publishing: 5] [Article Influence: 1.3] [Reference Citation Analysis]
46 Zheng X, Gai X, Ding F, Lu Z, Tu K, Yao Y, Liu Q. Histone acetyltransferase PCAF up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling. Mol Cancer 2013;12:96. [PMID: 23981651 DOI: 10.1186/1476-4598-12-96] [Cited by in Crossref: 29] [Cited by in F6Publishing: 26] [Article Influence: 3.2] [Reference Citation Analysis]
47 Thompson SM, Callstrom MR, Jondal DE, Butters KA, Knudsen BE, Anderson JL, Lien KR, Sutor SL, Lee JS, Thorgeirsson SS, Grande JP, Roberts LR, Woodrum DA. Heat Stress-Induced PI3K/mTORC2-Dependent AKT Signaling Is a Central Mediator of Hepatocellular Carcinoma Survival to Thermal Ablation Induced Heat Stress. PLoS One 2016;11:e0162634. [PMID: 27611696 DOI: 10.1371/journal.pone.0162634] [Cited by in Crossref: 13] [Cited by in F6Publishing: 16] [Article Influence: 2.2] [Reference Citation Analysis]
48 Zheng X, Song T, Dou C, Jia Y, Liu Q. CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. Oncotarget 2015;6:3752-69. [PMID: 25686837 DOI: 10.18632/oncotarget.2915] [Cited by in Crossref: 28] [Cited by in F6Publishing: 30] [Article Influence: 4.7] [Reference Citation Analysis]
49 Li J, He Y, Cao Y, Yu Y, Chen X, Gao X, Hu Q. Upregulation of Twist is involved in Gli1 induced migration and invasion of hepatocarcinoma cells. Biol Chem 2018;399:911-9. [PMID: 29908118 DOI: 10.1515/hsz-2018-0131] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 1.3] [Reference Citation Analysis]
50 Song T, Dou C, Jia Y, Tu K, Zheng X. TIMP-1 activated carcinoma-associated fibroblasts inhibit tumor apoptosis by activating SDF1/CXCR4 signaling in hepatocellular carcinoma. Oncotarget. 2015;6:12061-12079. [PMID: 25909286 DOI: 10.18632/oncotarget.3616] [Cited by in Crossref: 48] [Cited by in F6Publishing: 50] [Article Influence: 8.0] [Reference Citation Analysis]
51 Li L, Zhao J, Zhang Q, Tao Y, Shen C, Li R, Ma Z, Li J, Wang Z. Cancer Cell-Derived Exosomes Promote HCC Tumorigenesis Through Hedgehog Pathway. Front Oncol 2021;11:756205. [PMID: 34692546 DOI: 10.3389/fonc.2021.756205] [Reference Citation Analysis]