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For: Federico S, Pozzetti L, Papa A, Carullo G, Gemma S, Butini S, Campiani G, Relitti N. Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists. J Med Chem 2020;63:13466-513. [PMID: 32845153 DOI: 10.1021/acs.jmedchem.0c01049] [Cited by in Crossref: 40] [Cited by in F6Publishing: 46] [Article Influence: 13.3] [Reference Citation Analysis]
Number Citing Articles
1 Deng Y, Ren M, He P, Liu F, Wang X, Zhou C, Li Y, Yang S. Genetically engineered cell membrane-coated nanoparticles for antibacterial and immunoregulatory dual-function treatment of ligature-induced periodontitis. Front Bioeng Biotechnol 2023;11. [DOI: 10.3389/fbioe.2023.1113367] [Reference Citation Analysis]
2 Vaez H, Soraya H, Garjani A, Gholikhani T. Toll-Like Receptor 4 (TLR4) and AMPK Relevance in Cardiovascular Disease. Adv Pharm Bull 2023;13:36-47. [PMID: 36721803 DOI: 10.34172/apb.2023.004] [Reference Citation Analysis]
3 Zhang J, Zao X, Zhang J, Guo Z, Jin Q, Chen G, Gan D, Du H, Ye Y. Is it possible to intervene early cirrhosis by targeting toll-like receptors to rebalance the intestinal microbiome? Int Immunopharmacol 2022;115:109627. [PMID: 36577151 DOI: 10.1016/j.intimp.2022.109627] [Reference Citation Analysis]
4 Ghasempour M, Hosseini M, Soltani-Zangbar MS, Motavalli R, Aghebati-Maleki L, Dolati S, Mehdizadeh A, Yousefi M, Ahmadian Heris J. The impact of Hyssop (Hyssopus officinalis) extract on activation of endosomal toll like receptors and their downstream signaling pathways. BMC Res Notes 2022;15:366. [PMID: 36503515 DOI: 10.1186/s13104-022-06253-3] [Reference Citation Analysis]
5 Elegbeleye JA, Krishnamoorthy S, Bamidele OP, Adeyanju AA, Adebowale OJ, Agbemavor WSK. Health-promoting foods and food crops of West-Africa origin: The bioactive compounds and immunomodulating potential. J Food Biochem 2022;46:e14331. [PMID: 36448596 DOI: 10.1111/jfbc.14331] [Reference Citation Analysis]
6 Zhao L, Hou C, Yan N. Neuroinflammation in retinitis pigmentosa: Therapies targeting the innate immune system. Front Immunol 2022;13. [DOI: 10.3389/fimmu.2022.1059947] [Reference Citation Analysis]
7 Wang X, Wang Y, Zhu Y, Lei X, Zhang M, Li Y. Identification and immunological evaluation of novel TLR2 agonists through structural optimization of Diprovocim. Eur J Med Chem 2022;243:114771. [PMID: 36174413 DOI: 10.1016/j.ejmech.2022.114771] [Reference Citation Analysis]
8 Manan A, Pirzada RH, Haseeb M, Choi S. Toll-like Receptor Mediation in SARS-CoV-2: A Therapeutic Approach. IJMS 2022;23:10716. [DOI: 10.3390/ijms231810716] [Reference Citation Analysis]
9 George PJ, Marches R, Nehar-belaid D, Banchereau J, Lustigman S. The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways. Front Immunol 2022;13:961094. [DOI: 10.3389/fimmu.2022.961094] [Reference Citation Analysis]
10 Peng Y, Wang Y, Wang M, Lan J, Chen Y. Therapeutic applications of toll-like receptors (TLRs) agonists in AML. Clin Transl Oncol 2022. [PMID: 35962918 DOI: 10.1007/s12094-022-02917-5] [Reference Citation Analysis]
11 Das N, Bandopadhyay P, Roy S, Sinha BP, Dastidar UG, Rahaman O, Pal S, Ganguly D, Talukdar A. Development, Optimization, and In Vivo Validation of New Imidazopyridine Chemotypes as Dual TLR7/TLR9 Antagonists through Activity-Directed Sequential Incorporation of Relevant Structural Subunits. J Med Chem 2022. [PMID: 35959635 DOI: 10.1021/acs.jmedchem.2c00386] [Reference Citation Analysis]
12 Yang MH, Russell JL, Mifune Y, Wang Y, Shi H, Moresco EMY, Siegwart DJ, Beutler B, Boger DL. Next-Generation Diprovocims with Potent Human and Murine TLR1/TLR2 Agonist Activity That Activate the Innate and Adaptive Immune Response. J Med Chem 2022. [PMID: 35767437 DOI: 10.1021/acs.jmedchem.2c00419] [Reference Citation Analysis]
13 Rahimi Foroudi M, Yaghobi R, Afshari A, Roozbeh J, Miresmaeili SM, Javid A. The effect of BK polyomavirus large T antigen on CD4 and CD8 T cells in kidney transplant recipients. Transpl Immunol 2022;74:101655. [PMID: 35777612 DOI: 10.1016/j.trim.2022.101655] [Reference Citation Analysis]
14 Pal S, Ghosh Dastidar U, Ghosh T, Ganguly D, Talukdar A. Integration of Ligand-Based and Structure-Based Methods for the Design of Small-Molecule TLR7 Antagonists. Molecules 2022;27:4026. [DOI: 10.3390/molecules27134026] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
15 Huang L, Ge X, Liu Y, Li H, Zhang Z. The Role of Toll-like Receptor Agonists and Their Nanomedicines for Tumor Immunotherapy. Pharmaceutics 2022;14:1228. [PMID: 35745800 DOI: 10.3390/pharmaceutics14061228] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
16 Cen X, Wang B, Liang Y, Chen Y, Xiao Y, Du S, Nandakumar KS, Yin H, Liu S, Cheng K. Small molecule SMU-CX24 targeting Toll-like receptor 3 counteracts inflammation: A novel approach to atherosclerosis therapy. Acta Pharmaceutica Sinica B 2022. [DOI: 10.1016/j.apsb.2022.06.001] [Reference Citation Analysis]
17 Liu J, Zhang H, Su Y, Zhang B. Application and prospect of targeting innate immune sensors in the treatment of autoimmune diseases. Cell Biosci 2022;12:68. [PMID: 35619184 DOI: 10.1186/s13578-022-00810-w] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
18 Li X, Wu P, Yao J, Zhang K, Jin G, Algalil FA. Genistein Protects against Spinal Cord Injury in Mice by Inhibiting Neuroinflammation via TLR4-Mediated Microglial Polarization. Applied Bionics and Biomechanics 2022;2022:1-10. [DOI: 10.1155/2022/4790344] [Reference Citation Analysis]
19 Krishnan M, Choi J, Jang A, Choi S, Yeon J, Jang M, Lee Y, Son K, Shin SY, Jeong MS, Kim Y. Molecular mechanism underlying the TLR4 antagonistic and antiseptic activities of papiliocin, an insect innate immune response molecule. Proc Natl Acad Sci U S A 2022;119:e2115669119. [PMID: 35238667 DOI: 10.1073/pnas.2115669119] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
20 Chen ZP, Huang HP, He XY, Wu BZ, Liu Y. Early continuous blood purification affects TNF-α, IL-1β, and IL-6 in patients with severe acute pancreatitis via inhibiting TLR4 signaling pathway. Kaohsiung J Med Sci 2022. [PMID: 35049137 DOI: 10.1002/kjm2.12497] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
21 Chancharoenthana W, Leelahavanichkul A. Innate Immunity Response to BK Virus Infection in Polyomavirus-Associated Nephropathy in Kidney Transplant Recipients. Transplantology 2022;3:20-32. [DOI: 10.3390/transplantology3010003] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
22 Su S, Chen L, Yang M, Liang D, Ke B, Liu Z, Ke C, Liao G, Liu L, Luo X. Design, synthesis and immunological evaluation of monophosphoryl lipid A derivatives as adjuvants for a RBD-hFc based SARS-CoV-2 vaccine. RSC Med Chem 2022. [DOI: 10.1039/d2md00298a] [Reference Citation Analysis]
23 Joshi G, Borah P, Thakur S, Sharma P, Mayank, Poduri R. Exploring the COVID-19 vaccine candidates against SARS-CoV-2 and its variants: where do we stand and where do we go? Hum Vaccin Immunother 2021;:1-27. [PMID: 34856868 DOI: 10.1080/21645515.2021.1995283] [Cited by in Crossref: 7] [Cited by in F6Publishing: 4] [Article Influence: 3.5] [Reference Citation Analysis]
24 Plesa M, Gaudet M, Mogas A, Jalaleddine N, Halayko A, Al Heialy S, Hamid Q. Vitamin D3 Attenuates Viral-Induced Inflammation and Fibrotic Responses in Bronchial Smooth Muscle Cells. Front Immunol 2021;12:715848. [PMID: 34512638 DOI: 10.3389/fimmu.2021.715848] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
25 Sabnis RW. Spiro(isobenzofuranazetidine) Compounds for Treating Autoimmune Diseases. ACS Med Chem Lett 2021;12:1359-60. [PMID: 34531942 DOI: 10.1021/acsmedchemlett.1c00422] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
26 Sarkar A, Galasiti Kankanamalage AC, Zhang Q, Cheng H, Sivaprakasam P, Naglich J, Xie C, Gangwar S, Boger DL. Synthesis, structure-activity relationship studies and evaluation of a TLR 3/8/9 agonist and its analogues. Med Chem Res 2021;30:1377-85. [PMID: 34421287 DOI: 10.1007/s00044-021-02736-3] [Reference Citation Analysis]
27 Sabnis RW. Novel Carbazoles for Treating Inflammatory and Autoimmune Diseases. ACS Med Chem Lett 2021;12:1208-9. [PMID: 34413945 DOI: 10.1021/acsmedchemlett.1c00358] [Reference Citation Analysis]
28 Banstola A, Poudel K, Kim JO, Jeong JH, Yook S. Recent progress in stimuli-responsive nanosystems for inducing immunogenic cell death. J Control Release 2021;337:505-20. [PMID: 34314800 DOI: 10.1016/j.jconrel.2021.07.038] [Cited by in Crossref: 13] [Cited by in F6Publishing: 17] [Article Influence: 6.5] [Reference Citation Analysis]
29 Sabnis RW. Novel Triazatricycle Compounds for Treating Autoimmune Diseases. ACS Med Chem Lett 2021;12:1071-2. [PMID: 34267874 DOI: 10.1021/acsmedchemlett.1c00318] [Reference Citation Analysis]
30 Kundu B, Raychaudhuri D, Mukherjee A, Sinha BP, Sarkar D, Bandopadhyay P, Pal S, Das N, Dey D, Ramarao K, Nagireddy K, Ganguly D, Talukdar A. Systematic Optimization of Potent and Orally Bioavailable Purine Scaffold as a Dual Inhibitor of Toll-Like Receptors 7 and 9. J Med Chem 2021;64:9279-301. [PMID: 34142551 DOI: 10.1021/acs.jmedchem.1c00532] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
31 Talukdar A, Ganguly D, Roy S, Das N, Sarkar D. Structural Evolution and Translational Potential for Agonists and Antagonists of Endosomal Toll-like Receptors. J Med Chem 2021;64:8010-41. [PMID: 34107682 DOI: 10.1021/acs.jmedchem.1c00300] [Cited by in Crossref: 5] [Cited by in F6Publishing: 7] [Article Influence: 2.5] [Reference Citation Analysis]
32 Yang J, Hu F, Guo C, Liang Y, Song H, Cheng K. Discovery of isoliquiritigenin analogues that reverse acute hepatitis by inhibiting macrophage polarization. Bioorg Chem 2021;114:105043. [PMID: 34120019 DOI: 10.1016/j.bioorg.2021.105043] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
33 Lyu H, Elkins CM, Pierce JL, Serezani CH, Perrien DS. MyD88 Is Not Required for Muscle Injury-Induced Endochondral Heterotopic Ossification in a Mouse Model of Fibrodysplasia Ossificans Progressiva. Biomedicines 2021;9:630. [PMID: 34206078 DOI: 10.3390/biomedicines9060630] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
34 Pahlavanneshan S, Sayadmanesh A, Ebrahimiyan H, Basiri M. Toll-Like Receptor-Based Strategies for Cancer Immunotherapy. J Immunol Res 2021;2021:9912188. [PMID: 34124272 DOI: 10.1155/2021/9912188] [Cited by in Crossref: 15] [Cited by in F6Publishing: 19] [Article Influence: 7.5] [Reference Citation Analysis]
35 Kaushik D, Kaur A, Petrovsky N, Salunke DB. Structural evolution of toll-like receptor 7/8 agonists from imidazoquinolines to imidazoles. RSC Med Chem 2021;12:1065-120. [PMID: 34355178 DOI: 10.1039/d1md00031d] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 2.5] [Reference Citation Analysis]
36 Alhazmi HA, Najmi A, Javed SA, Sultana S, Al Bratty M, Makeen HA, Meraya AM, Ahsan W, Mohan S, Taha MME, Khalid A. Medicinal Plants and Isolated Molecules Demonstrating Immunomodulation Activity as Potential Alternative Therapies for Viral Diseases Including COVID-19. Front Immunol 2021;12:637553. [PMID: 34054806 DOI: 10.3389/fimmu.2021.637553] [Cited by in Crossref: 12] [Cited by in F6Publishing: 16] [Article Influence: 6.0] [Reference Citation Analysis]
37 Wang X, Liu Y, Han X, Zou G, Zhu W, Shen H, Liu H. Small molecule approaches to treat autoimmune and inflammatory diseases (Part II): Nucleic acid sensing antagonists and inhibitors. Bioorg Med Chem Lett 2021;44:128101. [PMID: 33984476 DOI: 10.1016/j.bmcl.2021.128101] [Cited by in Crossref: 2] [Cited by in F6Publishing: 5] [Article Influence: 1.0] [Reference Citation Analysis]
38 Kaushik D, Granato JT, Macedo GC, Dib PRB, Piplani S, Fung J, da Silva AD, Coimbra ES, Petrovsky N, Salunke DB. Toll-like receptor-7/8 agonist kill Leishmania amazonensis by acting as pro-oxidant and pro-inflammatory agent. J Pharm Pharmacol 2021;73:1180-90. [PMID: 33940589 DOI: 10.1093/jpp/rgab063] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
39 Mori T, Kataoka H, Into T. Effect of Myd88 deficiency on gene expression profiling in salivary glands of female non-obese diabetic (NOD) mice. J Oral Biosci 2021;63:192-8. [PMID: 33933610 DOI: 10.1016/j.job.2021.04.003] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
40 Namvar A, Bolhassani A, Javadi G, Noormohammadi Z. Combination of human papillomaviruses L1 and L2 multiepitope constructs protects mice against tumor cells. Fundam Clin Pharmacol 2021. [PMID: 33930201 DOI: 10.1111/fcp.12690] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
41 Miller S, Blanco MJ. Small molecule therapeutics for neuroinflammation-mediated neurodegenerative disorders. RSC Med Chem 2021;12:871-86. [PMID: 34223157 DOI: 10.1039/d1md00036e] [Cited by in Crossref: 2] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
42 Hasan MW, Haseeb M, Ehsan M, Gadahi JA, Wang Q, Memon MA, Aleem MT, Lakho SA, Yan RF, Xu LX, Song XK, Li X. The immunogenic maturation of goat monocyte-derived dendritic cells and upregulation of toll-like receptors by five antigens of Haemonchus contortus in-vitro. Res Vet Sci 2021;136:247-58. [PMID: 33721712 DOI: 10.1016/j.rvsc.2021.03.007] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
43 Sui H, Chen Q, Imamichi T. Cytoplasmic-translocated Ku70 senses intracellular DNA and mediates interferon-lambda1 induction. Immunology 2021;163:323-37. [PMID: 33548066 DOI: 10.1111/imm.13318] [Cited by in Crossref: 8] [Cited by in F6Publishing: 9] [Article Influence: 4.0] [Reference Citation Analysis]
44 Sabnis RW. Novel Hexahydro-1H-Pyrazino[1,2-a]pyrazine Compounds for Treating Autoimmune Diseases. ACS Med Chem Lett 2021;12:7-8. [PMID: 33488956 DOI: 10.1021/acsmedchemlett.0c00623] [Reference Citation Analysis]
45 Kaur A, Kaushik D, Piplani S, Mehta SK, Petrovsky N, Salunke DB. TLR2 Agonistic Small Molecules: Detailed Structure-Activity Relationship, Applications, and Future Prospects. J Med Chem 2021;64:233-78. [PMID: 33346636 DOI: 10.1021/acs.jmedchem.0c01627] [Cited by in Crossref: 12] [Cited by in F6Publishing: 13] [Article Influence: 4.0] [Reference Citation Analysis]
46 Kashani B, Zandi Z, Pourbagheri-Sigaroodi A, Bashash D, Ghaffari SH. The role of toll-like receptor 4 (TLR4) in cancer progression: A possible therapeutic target? J Cell Physiol 2021;236:4121-37. [PMID: 33230811 DOI: 10.1002/jcp.30166] [Cited by in Crossref: 24] [Cited by in F6Publishing: 26] [Article Influence: 8.0] [Reference Citation Analysis]