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For: Psaila B, Wang G, Rodriguez-Meira A, Li R, Heuston EF, Murphy L, Yee D, Hitchcock IS, Sousos N, O'Sullivan J, Anderson S, Senis YA, Weinberg OK, Calicchio ML, Iskander D, Royston D, Milojkovic D, Roberts I, Bodine DM, Thongjuea S, Mead AJ; NIH Intramural Sequencing Center. Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets. Mol Cell 2020;78:477-492.e8. [PMID: 32386542 DOI: 10.1016/j.molcel.2020.04.008] [Cited by in Crossref: 25] [Cited by in F6Publishing: 26] [Article Influence: 12.5] [Reference Citation Analysis]
Number Citing Articles
1 Wang G, Wen WX, Mead AJ, Roy A, Psaila B, Thongjuea S. Processing single-cell RNA-seq datasets using SingCellaR. STAR Protocols 2022;3:101266. [DOI: 10.1016/j.xpro.2022.101266] [Reference Citation Analysis]
2 Pemmaraju N, Chen NC, Verstovsek S. Immunotherapy and Immunomodulation in Myeloproliferative Neoplasms. Hematol Oncol Clin North Am 2021;35:409-29. [PMID: 33641877 DOI: 10.1016/j.hoc.2020.12.007] [Reference Citation Analysis]
3 Roweth HG, Battinelli EM. Lessons to learn from tumor-educated platelets. Blood 2021;137:3174-80. [PMID: 33940594 DOI: 10.1182/blood.2019003976] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
4 Estevez B, Borst S, Jarocha D, Sudunagunta V, Gonzalez M, Garifallou J, Hakonarson H, Gao P, Tan K, Liu P, Bagga S, Holdreith N, Tong W, Speck N, French DL, Gadue P, Poncz M. RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells. Blood 2021;137:2662-75. [PMID: 33569577 DOI: 10.1182/blood.2020006389] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 4.0] [Reference Citation Analysis]
5 Martelli F, Verachi P, Zingariello M, Mazzarini M, Vannucchi AM, Lonetti A, Bacci B, Sarli G, Migliaccio AR. hGATA1 Under the Control of a μLCR/β-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced by the Gata1 low Mutation in Mice. Front Genet 2021;12:720552. [PMID: 34707640 DOI: 10.3389/fgene.2021.720552] [Reference Citation Analysis]
6 Liu Y, Gu Z, Cao H, Kaphle P, Lyu J, Zhang Y, Hu W, Chung SS, Dickerson KE, Xu J. Convergence of oncogenic cooperation at single-cell and single-gene levels drives leukemic transformation. Nat Commun 2021;12:6323. [PMID: 34732703 DOI: 10.1038/s41467-021-26582-4] [Reference Citation Analysis]
7 Zhang P, Li X, Pan C, Zheng X, Hu B, Xie R, Hu J, Shang X, Yang H. Single-cell RNA sequencing to track novel perspectives in HSC heterogeneity. Stem Cell Res Ther 2022;13. [DOI: 10.1186/s13287-022-02718-1] [Reference Citation Analysis]
8 Krishnan A, Thomas S. Toward platelet transcriptomics in cancer diagnosis, prognosis and therapy. Br J Cancer 2021. [PMID: 34811507 DOI: 10.1038/s41416-021-01627-z] [Reference Citation Analysis]
9 Giardullo L, Altomare A, Rotondo C, Corrado A, Cantatore FP. Osteoblast Dysfunction in Non-Hereditary Sclerosing Bone Diseases. Int J Mol Sci 2021;22:7980. [PMID: 34360745 DOI: 10.3390/ijms22157980] [Reference Citation Analysis]
10 Huang D, Wang G, Ke Z, Zhou Y, Yang H, Ma T, Guan C. Megakaryocytes in pulmonary diseases. Life Sciences 2022. [DOI: 10.1016/j.lfs.2022.120602] [Reference Citation Analysis]
11 Iskander D, Wang G, Heuston EF, Christodoulidou C, Psaila B, Ponnusamy K, Ren H, Mokhtari Z, Robinson M, Chaidos A, Trivedi P, Trasanidis N, Katsarou A, Szydlo R, Palii CG, Zaidi MH, Al-Oqaily Q, Caputo VS, Roy A, Harrington Y, Karnik L, Naresh K, Mead AJ, Thongjuea S, Brand M, de la Fuente J, Bodine DM, Roberts I, Karadimitris A. Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia. Sci Transl Med 2021;13:eabf0113. [PMID: 34516827 DOI: 10.1126/scitranslmed.abf0113] [Reference Citation Analysis]
12 Thomas S, Krishnan A. Platelet Heterogeneity in Myeloproliferative Neoplasms. Arterioscler Thromb Vasc Biol 2021;41:2661-70. [PMID: 34615371 DOI: 10.1161/ATVBAHA.121.316373] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
13 Louka E, Povinelli B, Rodriguez-Meira A, Buck G, Wen WX, Wang G, Sousos N, Ashley N, Hamblin A, Booth CAG, Roy A, Elliott N, Iskander D, de la Fuente J, Fordham N, O'Byrne S, Inglott S, Norfo R, Salio M, Thongjuea S, Rao A, Roberts I, Mead AJ. Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia. J Exp Med 2021;218:e20180853. [PMID: 33416891 DOI: 10.1084/jem.20180853] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 6.0] [Reference Citation Analysis]
14 Nasillo V, Riva G, Paolini A, Forghieri F, Roncati L, Lusenti B, Maccaferri M, Messerotti A, Pioli V, Gilioli A, Bettelli F, Giusti D, Barozzi P, Lagreca I, Maffei R, Marasca R, Potenza L, Comoli P, Manfredini R, Maiorana A, Tagliafico E, Luppi M, Trenti T. Inflammatory Microenvironment and Specific T Cells in Myeloproliferative Neoplasms: Immunopathogenesis and Novel Immunotherapies. Int J Mol Sci 2021;22:1906. [PMID: 33672997 DOI: 10.3390/ijms22041906] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
15 Müller P, Baldauf CK, Haage TR, Waldleben AM, Richter F, Pfizenmaier K, Fischer T. Anti-inflammatory treatment in MPN: targeting TNFR1 and TNFR2 in JAK2-V617F-induced disease. Blood Adv 2021;5:5349-59. [PMID: 34592754 DOI: 10.1182/bloodadvances.2021004438] [Reference Citation Analysis]
16 Zhang X, Grimes HL. Why Single-Cell Sequencing Has Promise in MDS. Front Oncol 2021;11:769753. [PMID: 34926276 DOI: 10.3389/fonc.2021.769753] [Reference Citation Analysis]
17 Prins D, Park HJ, Watcham S, Li J, Vacca M, Bastos HP, Gerbaulet A, Vidal-Puig A, Göttgens B, Green AR. The stem/progenitor landscape is reshaped in a mouse model of essential thrombocythemia and causes excess megakaryocyte production. Sci Adv 2020;6:eabd3139. [PMID: 33239297 DOI: 10.1126/sciadv.abd3139] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
18 Melo-Cardenas J, Migliaccio AR, Crispino JD. The Role of Megakaryocytes in Myelofibrosis. Hematol Oncol Clin North Am 2021;35:191-203. [PMID: 33641863 DOI: 10.1016/j.hoc.2020.11.004] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
19 Olschok K, Han L, de Toledo MAS, Böhnke J, Graßhoff M, Costa IG, Theocharides A, Maurer A, Schüler HM, Buhl EM, Pannen K, Baumeister J, Kalmer M, Gupta S, Boor P, Gezer D, Brümmendorf TH, Zenke M, Chatain N, Koschmieder S. CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes. Stem Cell Reports 2021;16:2768-83. [PMID: 34678208 DOI: 10.1016/j.stemcr.2021.09.019] [Reference Citation Analysis]
20 Zhang Y, Huang Y, Hu L, Cheng T. New insights into Human Hematopoietic Stem and Progenitor Cells via Single-Cell Omics. Stem Cell Rev Rep 2022. [PMID: 35318612 DOI: 10.1007/s12015-022-10330-2] [Reference Citation Analysis]
21 Leimkühler NB, Costa IG, Schneider RK. From cell to cell: Identification of actionable targets in bone marrow fibrosis using single-cell technologies. Exp Hematol 2021;104:48-54. [PMID: 34601067 DOI: 10.1016/j.exphem.2021.09.006] [Reference Citation Analysis]
22 Roy A, Wang G, Iskander D, O'Byrne S, Elliott N, O'Sullivan J, Buck G, Heuston EF, Wen WX, Meira AR, Hua P, Karadimitris A, Mead AJ, Bodine DM, Roberts I, Psaila B, Thongjuea S. Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development. Cell Rep 2021;36:109698. [PMID: 34525349 DOI: 10.1016/j.celrep.2021.109698] [Reference Citation Analysis]
23 Strickland M, Quek L, Psaila B. The immune landscape in BCR-ABL negative myeloproliferative neoplasms: inflammation, infections and opportunities for immunotherapy. Br J Haematol 2021. [PMID: 34618358 DOI: 10.1111/bjh.17850] [Reference Citation Analysis]
24 Van Egeren D, Escabi J, Nguyen M, Liu S, Reilly CR, Patel S, Kamaz B, Kalyva M, DeAngelo DJ, Galinsky I, Wadleigh M, Winer ES, Luskin MR, Stone RM, Garcia JS, Hobbs GS, Camargo FD, Michor F, Mullally A, Cortes-Ciriano I, Hormoz S. Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms. Cell Stem Cell 2021;28:514-523.e9. [PMID: 33621486 DOI: 10.1016/j.stem.2021.02.001] [Cited by in Crossref: 15] [Cited by in F6Publishing: 22] [Article Influence: 15.0] [Reference Citation Analysis]
25 Greenfield G, McMullin MF, Mills K. Molecular pathogenesis of the myeloproliferative neoplasms. J Hematol Oncol 2021;14:103. [PMID: 34193229 DOI: 10.1186/s13045-021-01116-z] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
26 Marneth AE, Mullally A. Busy signal: platelet-derived growth factor activation in myelofibrosis. Haematologica 2020;105:1988-90. [PMID: 32739885 DOI: 10.3324/haematol.2020.253708] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
27 Tong J, Sun T, Ma S, Zhao Y, Ju M, Gao Y, Zhu P, Tan P, Fu R, Zhang A, Wang D, Wang D, Xiao Z, Zhou J, Yang R, Loughran SJ, Li J, Green AR, Bresnick EH, Wang D, Cheng T, Zhang L, Shi L. Hematopoietic Stem Cell Heterogeneity Is Linked to the Initiation and Therapeutic Response of Myeloproliferative Neoplasms. Cell Stem Cell 2021;28:502-513.e6. [PMID: 33621485 DOI: 10.1016/j.stem.2021.01.018] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
28 Pandey G, Kuykendall AT, Reuther GW. JAK2 inhibitor persistence in MPN: uncovering a central role of ERK activation. Blood Cancer J 2022;12:13. [PMID: 35082276 DOI: 10.1038/s41408-022-00609-5] [Reference Citation Analysis]
29 Ding L, Luo J, Zhang JP, Wang J, Li ZQ, Huang J, Chai L, Mu J, Zhao B, Zhong YR, Zhang LY, Liu L. Aberrant expression of SPAG6 may affect the disease phenotype and serve as a tumor biomarker in BCR/ABL1-negative myeloproliferative neoplasms. Oncol Lett 2022;23:10. [PMID: 34820009 DOI: 10.3892/ol.2021.13128] [Reference Citation Analysis]
30 Ramanathan G, Fleischman AG. The Microenvironment in Myeloproliferative Neoplasms. Hematol Oncol Clin North Am 2021;35:205-16. [PMID: 33641864 DOI: 10.1016/j.hoc.2020.11.003] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
31 Hua P, Roy N, de la Fuente J, Wang G, Thongjuea S, Clark K, Roy A, Psaila B, Ashley N, Harrington Y, Nerlov C, Watt SM, Roberts I, Davies JOJ. Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia. Blood 2019;134:2111-5. [PMID: 31697810 DOI: 10.1182/blood.2019002301] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 3.5] [Reference Citation Analysis]
32 Gleitz HFE, Benabid A, Schneider RK. Still a burning question: the interplay between inflammation and fibrosis in myeloproliferative neoplasms. Curr Opin Hematol 2021;28:364-71. [PMID: 34232140 DOI: 10.1097/MOH.0000000000000669] [Reference Citation Analysis]
33 Mughal TI, Psaila B, DeAngelo DJ, Saglio G, Van Etten RA, Radich JP. Interrogating the molecular genetics of chronic myeloproliferative malignancies for personalized management in 2021. Haematologica 2021;106:1787-93. [PMID: 33657787 DOI: 10.3324/haematol.2020.267252] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
34 Malara A, Di Buduo CA, Abbonante V, Balduini A. Bone marrow microenvironment of MPN cells. Int Rev Cell Mol Biol 2021;365:71-96. [PMID: 34756245 DOI: 10.1016/bs.ircmb.2021.07.001] [Reference Citation Analysis]
35 Mughal TI, Pemmaraju N, Psaila B, Radich J, Bose P, Lion T, Kiladjian JJ, Rampal R, Jain T, Verstovsek S, Yacoub A, Cortes JE, Mesa R, Saglio G, van Etten RA. Illuminating novel biological aspects and potential new therapeutic approaches for chronic myeloproliferative malignancies. Hematol Oncol 2020;38:654-64. [PMID: 32592408 DOI: 10.1002/hon.2771] [Reference Citation Analysis]
36 Chen TC, Yao CY, Chen YR, Yuan CT, Lin CC, Hsu YC, Chuang PH, Kao CJ, Li YH, Hou HA, Chou WC, Tien HF. Oncogenesis induced by combined Phf6 and Idh2 mutations through increased oncometabolites and impaired DNA repair. Oncogene 2022. [PMID: 35091680 DOI: 10.1038/s41388-022-02193-1] [Reference Citation Analysis]
37 Royston D, Mead AJ, Psaila B. Application of Single-Cell Approaches to Study Myeloproliferative Neoplasm Biology. Hematol Oncol Clin North Am 2021;35:279-93. [PMID: 33641869 DOI: 10.1016/j.hoc.2021.01.002] [Reference Citation Analysis]
38 Jutzi JS, Mullally A. Remodeling the Bone Marrow Microenvironment - A Proposal for Targeting Pro-inflammatory Contributors in MPN. Front Immunol 2020;11:2093. [PMID: 32983162 DOI: 10.3389/fimmu.2020.02093] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
39 Acosta J, Ssozi D, van Galen P. Single-Cell RNA Sequencing to Disentangle the Blood System. Arterioscler Thromb Vasc Biol 2021;41:1012-8. [PMID: 33441024 DOI: 10.1161/ATVBAHA.120.314654] [Cited by in Crossref: 4] [Cited by in F6Publishing: 1] [Article Influence: 4.0] [Reference Citation Analysis]
40 Penter L, Gohil SH, Huang T, Thrash EM, Schmidt D, Li S, Severgnini M, Neuberg D, Hodi FS, Livak KJ, Zeiser R, Bachireddy P, Wu CJ. Coevolving JAK2V617F+relapsed AML and donor T cells with PD-1 blockade after stem cell transplantation: an index case. Blood Adv 2021;5:4701-9. [PMID: 34432868 DOI: 10.1182/bloodadvances.2021004335] [Reference Citation Analysis]