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For: Ashour AE, Abd-Allah AR, Korashy HM, Attia SM, Alzahrani AZ, Saquib Q, Bakheet SA, Abdel-Hamied HE, Jamal S, Rishi AK. Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis. Mol Cell Biochem 2014;389:85-98. [PMID: 24399465 DOI: 10.1007/s11010-013-1930-1] [Cited by in Crossref: 46] [Cited by in F6Publishing: 40] [Article Influence: 5.8] [Reference Citation Analysis]
Number Citing Articles
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3 Ashour AE, Ahmed AF, Kumar A, Zoheir KM, Aboul-Soud MA, Ahmad SF, Attia SM, Abd-Allah AR, Cheryan VT, Rishi AK. Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-κB signaling and IL-8 expression. Mol Cell Biochem 2016;416:141-55. [PMID: 27084536 DOI: 10.1007/s11010-016-2703-4] [Cited by in Crossref: 27] [Cited by in F6Publishing: 26] [Article Influence: 4.5] [Reference Citation Analysis]
4 Ke X, Zhao Y, Lu X, Wang Z, Liu Y, Ren M, Lu G, Zhang D, Sun Z, Xu Z, Song JH, Cheng Y, Meltzer SJ, He S. TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling. Oncotarget 2015;6:32610-21. [PMID: 26416455 DOI: 10.18632/oncotarget.5362] [Reference Citation Analysis]
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10 Al-Hayali M, Garces A, Stocks M, Collins H, Bradshaw TD. Concurrent Reactive Oxygen Species Generation and Aneuploidy Induction Contribute to Thymoquinone Anticancer Activity. Molecules 2021;26:5136. [PMID: 34500570 DOI: 10.3390/molecules26175136] [Reference Citation Analysis]
11 Haron AS, Syed Alwi SS, Saiful Yazan L, Abd Razak R, Ong YS, Zakarial Ansar FH, Roshini Alexander H. Cytotoxic Effect of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) on Liver Cancer Cell Integrated with Hepatitis B Genome, Hep3B. Evid Based Complement Alternat Med 2018;2018:1549805. [PMID: 30186351 DOI: 10.1155/2018/1549805] [Cited by in Crossref: 9] [Cited by in F6Publishing: 7] [Article Influence: 2.3] [Reference Citation Analysis]
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13 Sheikh BY, Sarker MMR, Kamarudin MNA, Ismail A. Prophetic medicine as potential functional food elements in the intervention of cancer: A review. Biomedicine & Pharmacotherapy 2017;95:614-48. [DOI: 10.1016/j.biopha.2017.08.043] [Cited by in Crossref: 21] [Cited by in F6Publishing: 17] [Article Influence: 4.2] [Reference Citation Analysis]
14 Abd-rabou AA, Edris AE. Cytotoxic, apoptotic, and genetic evaluations of Nigella sativa essential oil nanoemulsion against human hepatocellular carcinoma cell lines. Cancer Nano 2021;12. [DOI: 10.1186/s12645-021-00101-y] [Reference Citation Analysis]
15 Ansary J, Giampieri F, Forbes-Hernandez TY, Regolo L, Quinzi D, Gracia Villar S, Garcia Villena E, Tutusaus Pifarre K, Alvarez-Suarez JM, Battino M, Cianciosi D. Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and Clinical Studies. Molecules 2021;26:2108. [PMID: 33916916 DOI: 10.3390/molecules26082108] [Reference Citation Analysis]
16 Mehanna MM, Sarieddine R, Alwattar JK, Chouaib R, Gali-Muhtasib H. Anticancer Activity of Thymoquinone Cubic Phase Nanoparticles Against Human Breast Cancer: Formulation, Cytotoxicity and Subcellular Localization. Int J Nanomedicine 2020;15:9557-70. [PMID: 33293807 DOI: 10.2147/IJN.S263797] [Cited by in Crossref: 5] [Cited by in F6Publishing: 2] [Article Influence: 2.5] [Reference Citation Analysis]
17 Sarkar C, Jamaddar S, Islam T, Mondal M, Islam MT, Mubarak MS. Therapeutic perspectives of the black cumin component thymoquinone: A review. Food Funct 2021;12:6167-213. [PMID: 34085672 DOI: 10.1039/d1fo00401h] [Reference Citation Analysis]
18 Jehan S, Zhong C, Li G, Zulqarnain Bakhtiar S, Li D, Sui G. Thymoquinone Selectively Induces Hepatocellular Carcinoma Cell Apoptosis in Synergism With Clinical Therapeutics and Dependence of p53 Status. Front Pharmacol. 2020;11:555283. [PMID: 33041795 DOI: 10.3389/fphar.2020.555283] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 2.5] [Reference Citation Analysis]
19 Bashir AO, El-mesery ME, Anwer R, Eissa LA. Thymoquinone potentiates miR-16 and miR-375 expressions in hepatocellular carcinoma. Life Sciences 2020;254:117794. [DOI: 10.1016/j.lfs.2020.117794] [Cited by in Crossref: 6] [Cited by in F6Publishing: 8] [Article Influence: 3.0] [Reference Citation Analysis]
20 Ali Abdalla YO, Subramaniam B, Nyamathulla S, Shamsuddin N, Arshad NM, Mun KS, Awang K, Nagoor NH, Mu J. Natural Products for Cancer Therapy: A Review of Their Mechanism of Actions and Toxicity in the Past Decade. Journal of Tropical Medicine 2022;2022:1-20. [DOI: 10.1155/2022/5794350] [Reference Citation Analysis]
21 Homayoonfal M, Asemi Z, Yousefi B. Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis. Cell Mol Biol Lett 2022;27:21. [PMID: 35236304 DOI: 10.1186/s11658-022-00320-0] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
22 Demiroren K, Basunlu MT, Erten R, Cokluk E. A comparison of the effects of thymoquinone, silymarin and N-acetylcysteine in an experimental hepatotoxicity. Biomed Pharmacother 2018;106:1705-12. [PMID: 30119245 DOI: 10.1016/j.biopha.2018.07.125] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
23 Venkataraman B, Almarzooqi S, Raj V, Alhassani AT, Alhassani AS, Ahmed KJ, Subramanian VS, Ojha SK, Attoub S, Adrian TE, Subramanya SB. Thymoquinone, a Dietary Bioactive Compound, Exerts Anti-Inflammatory Effects in Colitis by Stimulating Expression of the Colonic Epithelial PPAR-γ Transcription Factor. Nutrients 2021;13:1343. [PMID: 33920708 DOI: 10.3390/nu13041343] [Reference Citation Analysis]
24 Raut PK, Lee HS, Joo SH, Chun KS. Thymoquinone induces oxidative stress-mediated apoptosis through downregulation of Jak2/STAT3 signaling pathway in human melanoma cells. Food Chem Toxicol 2021;157:112604. [PMID: 34627931 DOI: 10.1016/j.fct.2021.112604] [Reference Citation Analysis]
25 Tabassum S, Thakur V, Rosli N, Ichwan SJA, Mishra P, Suriyah WH. Therapeutic implications of thymoquinone and its molecular and functional mechanisms against oral and lung cancer. Gene Reports 2022;27:101600. [DOI: 10.1016/j.genrep.2022.101600] [Reference Citation Analysis]
26 Elgohary S, Elkhodiry AA, Amin NS, Stein U, El Tayebi HM. Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients? Cells 2021;10:302. [PMID: 33540625 DOI: 10.3390/cells10020302] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
27 Rabea S, Alanazi FK, Ashour AE, Salem-Bekhit MM, Yassin AS, Moneib NA, Hashem AEM, Haq N. Salmonella-innovative targeting carrier: Loading with doxorubicin for cancer treatment. Saudi Pharm J 2020;28:1253-62. [PMID: 33132719 DOI: 10.1016/j.jsps.2020.08.016] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
28 Farooqi AA, Attar R, Xu B. Anticancer and Anti-Metastatic Role of Thymoquinone: Regulation of Oncogenic Signaling Cascades by Thymoquinone. IJMS 2022;23:6311. [DOI: 10.3390/ijms23116311] [Reference Citation Analysis]
29 Zadorozhna M, Tataranni T, Mangieri D. Piperine: role in prevention and progression of cancer. Mol Biol Rep 2019;46:5617-29. [PMID: 31273611 DOI: 10.1007/s11033-019-04927-z] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 4.7] [Reference Citation Analysis]
30 El-Sheikh AA, Morsy MA, Hamouda AH. Protective Mechanisms of Thymoquinone on Methotrexate-induced Intestinal Toxicity in Rats. Pharmacogn Mag 2016;12:S76-81. [PMID: 27041864 DOI: 10.4103/0973-1296.176106] [Cited by in Crossref: 14] [Cited by in F6Publishing: 15] [Article Influence: 2.3] [Reference Citation Analysis]
31 Şakalar Ç, İzgi K, İskender B, Sezen S, Aksu H, Çakır M, Kurt B, Turan A, Canatan H. The combination of thymoquinone and paclitaxel shows anti-tumor activity through the interplay with apoptosis network in triple-negative breast cancer. Tumour Biol 2016;37:4467-77. [PMID: 26500095 DOI: 10.1007/s13277-015-4307-0] [Cited by in Crossref: 36] [Cited by in F6Publishing: 33] [Article Influence: 5.1] [Reference Citation Analysis]
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33 Ke X, Zhao Y, Lu X, Wang Z, Liu Y, Ren M, Lu G, Zhang D, Sun Z, Xu Z, Song JH, Cheng Y, Meltzer SJ, He S. TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling. Oncotarget 2015;6:32610-21. [PMID: 26416455 DOI: 10.18632/oncotarget.5362] [Cited by in Crossref: 23] [Cited by in F6Publishing: 22] [Article Influence: 3.8] [Reference Citation Analysis]
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36 Homayoonfal M, Asemi Z, Yousefi B. Targeting microRNAs with thymoquinone: a new approach for cancer therapy. Cell Mol Biol Lett 2021;26:43. [PMID: 34627167 DOI: 10.1186/s11658-021-00286-5] [Reference Citation Analysis]
37 Haiaty S, Rashidi MR, Akbarzadeh M, Bazmany A, Mostafazadeh M, Nikanfar S, Zibaei Z, Rahbarghazi R, Nouri M. Thymoquinone inhibited vasculogenic capacity and promoted mesenchymal-epithelial transition of human breast cancer stem cells. BMC Complement Med Ther 2021;21:83. [PMID: 33663486 DOI: 10.1186/s12906-021-03246-w] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
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41 Ismail N, Abdel–mottaleb Y, Eissa Ahmed AA, El-maraghy NN. Novel combination of thymoquinone and resveratrol enhances anticancer effect on hepatocellular carcinoma cell line. Future Journal of Pharmaceutical Sciences 2018;4:41-6. [DOI: 10.1016/j.fjps.2017.08.001] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
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43 Khan AW, Farooq M, Haseeb M, Choi S. Role of Plant-Derived Active Constituents in Cancer Treatment and Their Mechanisms of Action. Cells 2022;11:1326. [DOI: 10.3390/cells11081326] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
44 Alam M, Hasan GM, Ansari MM, Sharma R, Yadav DK, Hassan MI. Therapeutic implications and clinical manifestations of thymoquinone. Phytochemistry 2022. [DOI: 10.1016/j.phytochem.2022.113213] [Reference Citation Analysis]
45 Hu X, Ma J, Vikash V, Li J, Wu D, Liu Y, Zhang J, Dong W. Thymoquinone Augments Cisplatin-Induced Apoptosis on Esophageal Carcinoma Through Mitigating the Activation of JAK2/STAT3 Pathway. Dig Dis Sci. 2018;63:126-134. [PMID: 29197940 DOI: 10.1007/s10620-017-4856-8] [Cited by in Crossref: 15] [Cited by in F6Publishing: 16] [Article Influence: 3.0] [Reference Citation Analysis]
46 Aslan M, Afşar E, Kırımlıoglu E, Çeker T, Yılmaz Ç. Antiproliferative Effects of Thymoquinone in MCF-7 Breast and HepG2 Liver Cancer Cells: Possible Role of Ceramide and ER Stress. Nutr Cancer 2021;73:460-72. [PMID: 32286088 DOI: 10.1080/01635581.2020.1751216] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 4.0] [Reference Citation Analysis]
47 Zhang B, Ting WJ, Gao J, Kang ZF, Huang CY, Weng YJ. Erk phosphorylation reduces the thymoquinone toxicity in human hepatocarcinoma. Environ Toxicol 2021;36:1990-8. [PMID: 34173702 DOI: 10.1002/tox.23317] [Reference Citation Analysis]
48 Gomathinayagam R, Ha JH, Jayaraman M, Song YS, Isidoro C, Dhanasekaran DN. Chemopreventive and Anticancer Effects of Thymoquinone: Cellular and Molecular Targets. J Cancer Prev 2020;25:136-51. [PMID: 33033708 DOI: 10.15430/JCP.2020.25.3.136] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.5] [Reference Citation Analysis]
49 Zhang R, Wu T, Zheng P, Liu M, Xu G, Xi M, Yu J. Thymoquinone sensitizes human hepatocarcinoma cells to TRAIL-induced apoptosis via oxidative DNA damage. DNA Repair (Amst) 2021;103:103117. [PMID: 33990030 DOI: 10.1016/j.dnarep.2021.103117] [Reference Citation Analysis]
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