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For: Kubo N, Araki K, Kuwano H, Shirabe K. Cancer-associated fibroblasts in hepatocellular carcinoma. World J Gastroenterol 2016; 22(30): 6841-6850 [PMID: 27570421 DOI: 10.3748/wjg.v22.i30.6841]
URL: https://www.wjgnet.com/1948-5182/full/v22/i30/6841.htm
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Xin Jin, Haida Shi, Zhi Li, Huixing Li, Huanxian Ma, Xianjie Shi, Mingjun Zheng. Characterizing PTP4A3/PRL-3 as the Potential Prognostic Marker Gene for Liver Hepatocellular CarcinomaJournal of Oncology 2022; 2022: 1 doi: 10.1155/2022/2717056
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Difeng Li, Xin Zhang, Lili Jiang. Molecular mechanism and potential therapeutic targets of liver metastasis from gastric cancerFrontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.1000807
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Leonard Kaps, Detlef Schuppan. Targeting Cancer Associated Fibroblasts in Liver Fibrosis and Liver Cancer Using NanocarriersCells 2020; 9(9): 2027 doi: 10.3390/cells9092027
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Jun Zhang, Yuliang Pan, Long Jin, Huiyun Yang, Peiguo Cao. Exosomal‐miR‐522‐3p derived from cancer‐associated fibroblasts accelerates tumor metastasis and angiogenesis via repression bone morphogenetic protein 5 in colorectal cancerJournal of Gastroenterology and Hepatology 2024; 39(1): 107 doi: 10.1111/jgh.16345
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Rui Feng, Yuji Morine, Tetsuya Ikemoto, Satoru Imura, Shuichi Iwahashi, Yu Saito, Mitsuo Shimada. Nab‐paclitaxel interrupts cancer‐stromal interaction through C‐X‐C motif chemokine 10‐mediated interleukin‐6 downregulation in vitroCancer Science 2018; 109(8): 2509 doi: 10.1111/cas.13694
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Jian Guo, Huating Zeng, Yan Chen. Emerging Nano Drug Delivery Systems Targeting Cancer-Associated Fibroblasts for Improved Antitumor Effect and Tumor Drug PenetrationMolecular Pharmaceutics 2020; 17(4): 1028 doi: 10.1021/acs.molpharmaceut.0c00014
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Yi-Chang Wang, Yu-Syuan Wu, Chia-Yang Hung, Shao-An Wang, Ming-Jer Young, Tsung-I Hsu, Jan-Jong Hung. USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancyNature Communications 2018; 9(1) doi: 10.1038/s41467-018-06178-1
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Shaoshi Zhang, Wendi Bacon, Maikel P. Peppelenbosch, Folkert van Kemenade, Andrew Peter Stubbs. Deciphering Tumour Microenvironment of Liver Cancer through Deconvolution of Bulk RNA-Seq Data with Single-Cell AtlasCancers 2022; 15(1): 153 doi: 10.3390/cancers15010153
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Hyungjin Rhee, Hye-Young Kim, Ji-Hye Choi, Hyun Goo Woo, Jeong Eun Yoo, Ji Hae Nahm, Jin-Sub Choi, Young Nyun Park. Keratin 19 Expression in Hepatocellular Carcinoma Is Regulated by Fibroblast-Derived HGF via a MET-ERK1/2-AP1 and SP1 AxisCancer Research 2018; 78(7): 1619 doi: 10.1158/0008-5472.CAN-17-0988
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Hidenori Shiraha, Masaya Iwamuro, Hiroyuki Okada. Tumor MicroenvironmentAdvances in Experimental Medicine and Biology 2020; 1234: 43 doi: 10.1007/978-3-030-37184-5_4
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Qiang Yuan, Yi Chu, Xiaoyu Li, Yunshu Shi, Yingying Chen, Jimin Zhao, Jing Lu, Kangdong Liu, Yaping Guo. CAFrgDB: a database for cancer-associated fibroblasts related genes and their functions in cancerCancer Gene Therapy 2023; 30(6): 917 doi: 10.1038/s41417-023-00603-4
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Siming Gong, Changwu Wu, Yingjuan Duan, Juyu Tang, Panfeng Wu. A Comprehensive Pan-Cancer Analysis for Pituitary Tumor-Transforming Gene 1Frontiers in Genetics 2022; 13 doi: 10.3389/fgene.2022.843579
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Zhong-Yang Jiang, Xi-Mei Ma, Xiao-Hui Luan, Zhen-Yu Liuyang, Yi-Yang Hong, Yuan Dai, Qing-Hua Dong, Guan-Yu Wang. BMI-1 activates hepatic stellate cells to promote the epithelial-mesenchymal transition of colorectal cancer cellsWorld Journal of Gastroenterology 2023; 29(23): 3606-3621 doi: 10.3748/wjg.v29.i23.3606
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Massimiliano Berretta, Luca Rinaldi, Fabrizio Di Benedetto, Arben Lleshi, Vallì De Re, Gaetano Facchini, Paolo De Paoli, Raffaele Di Francia. Angiogenesis Inhibitors for the Treatment of Hepatocellular CarcinomaFrontiers in Pharmacology 2016; 7 doi: 10.3389/fphar.2016.00428
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Antonio Sircana, Elena Paschetta, Francesca Saba, Federica Molinaro, Giovanni Musso. Recent Insight into the Role of Fibrosis in Nonalcoholic Steatohepatitis-Related Hepatocellular CarcinomaInternational Journal of Molecular Sciences 2019; 20(7): 1745 doi: 10.3390/ijms20071745
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Gurbet Celik-Turgut, Nazmiye Olmez, Tugba Koc, Ozden Ozgun-Acar, Asli Semiz, Yavuz Dodurga, Naciye Lale Satiroglu-Tufan, Alaattin Sen. Role of AHR, NF-kB and CYP1A1 crosstalk with the X protein of Hepatitis B virus in hepatocellular carcinoma cellsGene 2023; 853: 147099 doi: 10.1016/j.gene.2022.147099
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Yiming Shen, Zhengyu Wei, Chongchang Zhou, Jiangping Song, Jianing Wang, Jiada Wang, Linrong Wu, Shenzhe Fang, Zhisen Shen. Arylsulfatase I is a prognostic biomarker for head and neck squamous cell carcinoma and Pan‐cancerJournal of Clinical Laboratory Analysis 2022; 36(9) doi: 10.1002/jcla.24600
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Xingcheng Xiong, Juanli Xi, Qian Liu, Cixiao Wang, Zeyou Jiang, Su‐Yang Yue, Lei Shi, Yuping Rong, Carmen Berasain. Co‐expression of IL‐7 and PH20 promote anti‐GPC3 CAR‐T tumour suppressor activity in vivo and in vitroLiver International 2021; 41(5): 1033 doi: 10.1111/liv.14771
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Jacek R. Wilczyński. Interaction of Immune and Cancer CellsExperientia Supplementum 2022; 113: 219 doi: 10.1007/978-3-030-91311-3_8
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Lushan Peng, Dan Wang, Yingying Han, Tao Huang, Xiaoyun He, Junpu Wang, Chunlin Ou. Emerging Role of Cancer-Associated Fibroblasts-Derived Exosomes in TumorigenesisFrontiers in Immunology 2022; 12 doi: 10.3389/fimmu.2021.795372
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Yang-Hsiang Lin, Meng-Han Wu, Chau-Ting Yeh, Kwang-Huei Lin. Long Non-Coding RNAs as Mediators of Tumor Microenvironment and Liver Cancer Cell CommunicationInternational Journal of Molecular Sciences 2018; 19(12): 3742 doi: 10.3390/ijms19123742
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Hamidreza Zalpoor, Fatemeh Aziziyan, Mahsa Liaghat, Maryam Bakhtiyari, Abdullatif Akbari, Mohsen Nabi-Afjadi, Razieh Forghaniesfidvajani, Nima Rezaei. The roles of metabolic profiles and intracellular signaling pathways of tumor microenvironment cells in angiogenesis of solid tumorsCell Communication and Signaling 2022; 20(1) doi: 10.1186/s12964-022-00951-y
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Longfei Xiao, Zihui Wang, Ning Lu, Huawei Wei, Jian Kang, Mengyi Yuan, Xihui Sheng, Xiaolong Qi, Kai Xing, Yong Guo, Xiangguo Wang, Junjin Zhao, Yuping Gao, Hemin Ni. Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cellsThe Journal of Steroid Biochemistry and Molecular Biology 2022; 216: 106041 doi: 10.1016/j.jsbmb.2021.106041
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Ka‐Hei Lam, Stephanie Ma. Noncellular components in the liver cancer stem cell niche: Biology and potential clinical implicationsHepatology 2023; 78(3): 991 doi: 10.1002/hep.32629
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Xian Zhong, Haiyi Long, Lili Chen, Yuhua Xie, Yifan Shi, Jianyun Peng, Ruiying Zheng, Liya Su, Yu Duan, Xiaoyan Xie, Manxia Lin. Stiffness on shear wave elastography as a potential microenvironment biomarker for predicting tumor recurrence in HBV-related hepatocellular carcinomaInsights into Imaging 2023; 14(1) doi: 10.1186/s13244-023-01505-7
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Antonella Argentiero, Antonella Delvecchio, Rossella Fasano, Alessandro Andriano, Ingrid Catalina Caradonna, Riccardo Memeo, Vanessa Desantis. The Complexity of the Tumor Microenvironment in Hepatocellular Carcinoma and Emerging Therapeutic DevelopmentsJournal of Clinical Medicine 2023; 12(23): 7469 doi: 10.3390/jcm12237469
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Srinivas Pittala, Yakov Krelin, Varda Shoshan-Barmatz. Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based PeptideNeoplasia 2018; 20(6): 594 doi: 10.1016/j.neo.2018.02.012
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Qingyu Cui, Bixiao Wang, Kaifu Li, Haichen Sun, Tao Hai, Yan Zhang, Hua Kang. Upregulating MMP‑1 in carcinoma‑associated fibroblasts reduces the efficacy of Taxotere on breast cancer synergized by Collagen IVOncology Letters 2018;  doi: 10.3892/ol.2018.9092
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Kumar Jayant, Nagy Habib, Kai W. Huang, Jane Warwick, Ramesh Arasaradnam. Recent Advances: The Imbalance of Immune Cells and Cytokines in the Pathogenesis of Hepatocellular CarcinomaDiagnostics 2020; 10(5): 338 doi: 10.3390/diagnostics10050338
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Asmaa F. Khafaga, Shaker A. Mousa, Lotfi Aleya, Mohamed M. Abdel-Daim. Three-dimensional (3D) cell culture: a valuable step in advancing treatments for human hepatocellular carcinomaCancer Cell International 2022; 22(1) doi: 10.1186/s12935-022-02662-3
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Weijie Deng, Peng Zhu, Huixuan Xu, Xianliang Hou, Wenbiao Chen, Zhiqian Zhang. Classification and Prognostic Characteristics of Hepatocellular Carcinoma Based on Glycolysis Cholesterol Synthesis AxisJournal of Oncology 2022; 2022: 1 doi: 10.1155/2022/2014625
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Norihiro Ishii, Kenichiro Araki, Takehiko Yokobori, Kei Hagiwara, Dorgormaa Gantumur, Takahiro Yamanaka, Tadashi Handa, Mariko Tsukagoshi, Takamichi Igarashi, Akira Watanabe, Norio Kubo, Norifumi Harimoto, Atsushi Masamune, Kazuo Umezawa, Hiroyuki Kuwano, Ken Shirabe. Conophylline suppresses pancreatic cancer desmoplasia and cancer‐promoting cytokines produced by cancer‐associated fibroblastsCancer Science 2019; 110(1): 334 doi: 10.1111/cas.13847
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Siqi Chen, Yaqing Du, Xin-Yuan Guan, Qian Yan. The current status of tumor microenvironment and cancer stem cells in sorafenib resistance of hepatocellular carcinomaFrontiers in Oncology 2023; 13 doi: 10.3389/fonc.2023.1204513
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Devis Pascut, Muhammad Yogi Pratama, Niem V.T. Vo, Rina Masadah, Claudio Tiribelli. The Crosstalk between Tumor Cells and the Microenvironment in Hepatocellular Carcinoma: The Role of Exosomal microRNAs and Their Clinical ImplicationsCancers 2020; 12(4): 823 doi: 10.3390/cancers12040823
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Lotte D. de Hosson, Tim J. Takkenkamp, Gursah Kats-Ugurlu, Grietje Bouma, Marian Bulthuis, Elisabeth G. E. de Vries, Martijn van Faassen, Ido P. Kema, Annemiek M. E. Walenkamp. Neuroendocrine tumours and their microenvironmentCancer Immunology, Immunotherapy 2020; 69(8): 1449 doi: 10.1007/s00262-020-02556-1
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Takahiro Kubo, Norihisa Nishimura, Kosuke Kaji, Fumimasa Tomooka, Akihiko Shibamoto, Satoshi Iwai, Junya Suzuki, Hideto Kawaratani, Tadashi Namisaki, Takemi Akahane, Hitoshi Yoshiji. Role of Epiregulin on Lipopolysaccharide-Induced Hepatocarcinogenesis as a Mediator via EGFR Signaling in the Cancer MicroenvironmentInternational Journal of Molecular Sciences 2024; 25(8): 4405 doi: 10.3390/ijms25084405
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Nilu Dhungel, Reneau Youngblood, Min Chu, Jennifer Carroll, Ana-Maria Dragoi. Assessing the epithelial-to-mesenchymal plasticity in a small cell lung carcinoma (SCLC) and lung fibroblasts co-culture modelFrontiers in Molecular Biosciences 2023; 10 doi: 10.3389/fmolb.2023.1096326
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Bin Huang, Manping Huang, Qin Li. Cancer-Associated Fibroblasts Promote Angiogenesis of Hepatocellular Carcinoma by VEGF-Mediated EZH2/VASH1 PathwayTechnology in Cancer Research & Treatment 2019; 18: 153303381987990 doi: 10.1177/1533033819879905
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Natasha Zulaziz, San Jiun Chai, Kue Peng Lim. The origins, roles and therapies of cancer associated fibroblast in liver cancerFrontiers in Oncology 2023; 13 doi: 10.3389/fonc.2023.1151373
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Jelena Radić, Bojana Kožik, Ivan Nikolić, Ivana Kolarov-Bjelobrk, Tijana Vasiljević, Bojana Vranjković, Sanja Despotović. Multiple Roles of LOXL2 in the Progression of Hepatocellular Carcinoma and Its Potential for Therapeutic TargetingInternational Journal of Molecular Sciences 2023; 24(14): 11745 doi: 10.3390/ijms241411745
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Jiaqian Han, Xiaobo Xu, Zi Liu, Zengqiang Li, Yingliang Wu, Daiying Zuo. Recent advances of molecular mechanisms of regulating PD-L1 expression in melanomaInternational Immunopharmacology 2020; 88: 106971 doi: 10.1016/j.intimp.2020.106971
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Francesco Dituri, Matteo Centonze, Erwin J. W. Berenschot, Niels R. Tas, Arturo Susarrey-Arce, Silke Krol. Complex Tumor Spheroid Formation and One-Step Cancer-Associated Fibroblasts Purification from Hepatocellular Carcinoma Tissue Promoted by Inorganic Surface TopographyNanomaterials 2021; 11(12): 3233 doi: 10.3390/nano11123233
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Junki Maehara, Yohei Masugi, Tokiya Abe, Hanako Tsujikawa, Yutaka Kurebayashi, Akihisa Ueno, Hidenori Ojima, Shigeo Okuda, Masahiro Jinzaki, Masahiro Shinoda, Yuko Kitagawa, Yoshinao Oda, Hiroshi Honda, Michiie Sakamoto. Quantification of intratumoral collagen and elastin fibers within hepatocellular carcinoma tissues finds correlations with clinico‐patho‐radiological featuresHepatology Research 2020; 50(5): 607 doi: 10.1111/hepr.13484
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Xiaocheng Zhou, Tinglin Yan, Chunming Huang, Zhi Xu, Lin Wang, Erhui Jiang, Hui Wang, Yang Chen, Ke Liu, Zhe Shao, Zhengjun Shang. Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathwayJournal of Experimental & Clinical Cancer Research 2018; 37(1) doi: 10.1186/s13046-018-0911-3
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Yanying Li, Jingliang Wu, Qiao Lu, Xuemin Liu, Jiaxuan Wen, Xiaohui Qi, Jianhao Liu, Bo Lian, Bo Zhang, Hengyi Sun, Guixiang Tian. GA&HA-Modified Liposomes for Co-Delivery of Aprepitant and Curcumin to Inhibit Drug-Resistance and Metastasis of Hepatocellular CarcinomaInternational Journal of Nanomedicine 2022; : 2559 doi: 10.2147/IJN.S366180
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Jianming Hu, Leyi Zhang, Wuzhen Chen, Lesang Shen, Jingxin Jiang, Shanshan Sun, Zhigang Chen. Role of Intra- and Extracellular Lipid Signals in Cancer Stemness and Potential Therapeutic StrategyFrontiers in Pharmacology 2021; 12 doi: 10.3389/fphar.2021.730751
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Lawrence M Agius. Dimensions of Niche-Induced Anti-Apoptosis of Therapeutically Resistant Neoplasms in Radio-Chemo-TherapyInternational Journal of Radiology & Radiation Therapy 2017; 2(3) doi: 10.15406/ijrrt.2017.02.00026
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Ning Zhang, Long-Rong Wang, Dou-Dou Li, De-Ning Ma, Cheng-Hao Wang, Xi-Gan He, Dong-Mei Gao, Lu Wang, Zhao-You Tang. Interferon-α Combined With Herbal Compound “Songyou Yin” Effectively Inhibits the Increased Invasiveness and Metastasis by Insufficient Radiofrequency Ablation of Hepatocellular Carcinoma in an Animal ModelIntegrative Cancer Therapies 2018; 17(4): 1260 doi: 10.1177/1534735418801525
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Fugen Takagi, Motomasa Furuse, Hiroko Kuwabara, Akihiro Kambara, Naoki Omura, Shogo Tanabe, Ryokichi Yagi, Ryo Hiramatsu, Masahiro Kameda, Naosuke Nonoguchi, Shinji Kawabata, Toshihiro Takami, Shin‐Ichi Miyatake, Masahiko Wanibuchi. Expression and distribution of hypoxia‐inducible factor‐1α and vascular endothelial growth factor in comparison between radiation necrosis and tumor tissue in metastatic brain tumor: A case reportNeuropathology 2023;  doi: 10.1111/neup.12958
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Chun-Feng Xie, Kun-Liang Feng, Ji-Nan Wang, Rui Luo, Chong-Kai Fang, Ying Zhang, Chuang-Peng Shen, Chong Zhong. Jianpi Huayu decoction inhibits the epithelial–mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signalingJournal of Ethnopharmacology 2022; 294: 115360 doi: 10.1016/j.jep.2022.115360
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Melissa Borgia, Michele Dal Bo, Giuseppe Toffoli. Role of Virus-Related Chronic Inflammation and Mechanisms of Cancer Immune-Suppression in Pathogenesis and Progression of Hepatocellular CarcinomaCancers 2021; 13(17): 4387 doi: 10.3390/cancers13174387
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Wei Li, Qiang Fu, Wenling Man, Huanqing Guo, Po Yang. LncRNA OR3A4 participates in the angiogenesis of hepatocellular carcinoma through modulating AGGF1/akt/mTOR pathwayEuropean Journal of Pharmacology 2019; 849: 106 doi: 10.1016/j.ejphar.2019.01.049
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Avijit Paul, Yakov Krelin, Tasleem Arif, Rina Jeger, Varda Shoshan-Barmatz. A New Role for the Mitochondrial Pro-apoptotic Protein SMAC/Diablo in Phospholipid Synthesis Associated with TumorigenesisMolecular Therapy 2018; 26(3): 680 doi: 10.1016/j.ymthe.2017.12.020
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Yuting Gao, Yi Gong, Junlan Lu, Huiqin Hao, Xinli Shi. Targeting YAP1 to improve the efficacy of immune checkpoint inhibitors in liver cancer: mechanism and strategyFrontiers in Immunology 2024; 15 doi: 10.3389/fimmu.2024.1377722
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Jie Zhao, Shaobo Yang, Caihong Lv, Ying Liu. Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1American Journal of Physiology-Cell Physiology 2023; 324(5): C1039 doi: 10.1152/ajpcell.00454.2022
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Qing Li, Chun-Chao Zhu, Bo Ni, Zi-Zhen Zhang, Shu-Heng Jiang, Li-Peng Hu, Xu Wang, Xiao-Xin Zhang, Pei-Qi Huang, Qin Yang, Jun Li, Jian-Ren Gu, Jia Xu, Kathy Qian Luo, Gang Zhao, Zhi-Gang Zhang. Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblastseBioMedicine 2019; 49: 157 doi: 10.1016/j.ebiom.2019.10.037
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Hiroyuki Kuwano, Takehiko Yokobori, Tatsuya Miyazaki, Makoto Sohda, Tomonori Yoshida, Yoko Azuma, Hironori Tatsuki, Yasunari Ubukata, Nobuhiro Nakazawa, Kengo Kuriyama, Akihiko Sano, Makoto Sakai, Hiroomi Ogawa, Hiroshi Saeki, Ken Shirabe. Field carcinogenesis and biological significance of the potential of the bystander effect: carcinogenesis, therapeutic response, and tissue regenerationSurgery Today 2023; 53(5): 545 doi: 10.1007/s00595-022-02524-5
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Hao Wang, Wenwei Zhu, Shuhua Ren, Yanyan Kong, Qi Huang, Jun Zhao, Yihui Guan, Huliang Jia, Jinhong Chen, Lu Lu, Fang Xie, Lunxiu Qin. 68Ga-FAPI-04 Versus 18F-FDG PET/CT in the Detection of Hepatocellular CarcinomaFrontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.693640
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Thuc Ly, Gunjan Gaur, Sufi Mary Thomas. Autophagy and Metabolism2022; : 163 doi: 10.1016/B978-0-323-99879-6.00004-3
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Xian Zhong, Lili Chen, Haiyi Long, Ruiying Zheng, Liya Su, Yu Duan, Xiaoyan Xie, Manxia Lin. The “stiff rim” sign of hepatocellular carcinoma on shear wave elastography: correlation with pathological features and potential prognostic valueAbdominal Radiology 2022; 47(12): 4115 doi: 10.1007/s00261-022-03628-9
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