Research interest include molecular mechanisms that maintain stemness, and induce differentiation in stem cells. Bone marrow, adipose, and human umbilical cord derived mesenchymal stem cells have the potential to self-renew and capability to differentiate. Dr. Khan’s interest includes producing cardiovascular injury, its characterization and repair with stem cells. He is currently working on tissue engineering based approach for osteochondral regeneration with stem cells. He is also interested to establish GMP for human umbilical cord derived stem cells in Pakistan, and transform current basic stem cell research into translational medicine.  Future interests include direct differentiation and trans-differentiation of stem cells with help of chemicals, genetic and epigenetic modification to neurons, cardiomyocytes, insulin secreting beta cells, and to skin fibroblast.