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世界华人消化杂志. 2024-10-28; 32(10): 767-773
在线出版 2024-10-28. doi: 10.11569/wcjd.v32.i10.767
表1 3组一般资料对比[(mean±SD)/n(%)]
组别例数男/女年龄(岁)体质量指数(kg/m2)病因
消化性溃疡上消化道良性肿瘤上消化道黏膜炎症其他
A组4424/2039.48±5.1423.48±2.1916(36.36)11(25.00)10(22.73)7(15.91)
B组4426/1840.15±5.2823.07±2.4418(40.91)8(18.18)9(20.45)9(20.45)
C组4423/2139.77±4.9622.79±22.1019(43.18)10(22.73)7(15.91)8(18.18)
t/χ2/u0.7330.1890.0321.535
P0.6930.8280.9690.957
表2 3组即时止血有效率对比n(%)
组别例数完全止血基本止血未止血有效率
A组4415(34.09)14(31.82)15(34.09)29(65.91)
B组4418(40.91)18(40.91)8(18.18)36(81.82)
C组4425(56.82)17(38.64)2(4.55)42(95.45)ab
χ29.583
P0.008
表3 3组症状改善情况对比(mean±SD)/n(%)
组别例数出血停止时间(h)黑便消失时间(h)住院时间(d)再出血率
A组4413.15±2.0114.45±2.189.44±1.867(15.91)
B组4410.14±1.89a10.79±1.38a8.04±2.06a4(9.09)
C组448.49±2.15ab9.05±1.95ab6.48±1.79ab0(0.00)ab
F/χ260.23595.87926.5347.339
P<0.001<0.001<0.0010.026
表4 3组凝血功能对比(mean±SD)
时间组别例数PT(s)APTT(s)D-D(mg/L)FIB(g/L)
治疗前A组4415.24±0.8236.42±3.152.15±0.512.37±0.39
B组4415.19±0.7936.71±4.012.09±0.482.35±0.41
C组4415.53±0.8336.68±3.752.13±0.532.40±0.38
F2.2410.0840.1600.180
P0.1110.9200.8530.836
治疗后A组4412.23±0.47a31.50±3.71a1.23±0.23a2.88±0.47a
B组4411.94±0.64ab28.41±3.68ab1.01±0.19ab3.26±0.41ab
C组4411.21±0.51abc25.98±3.44abc0.79±0.20abc3.65±0.48abc
F40.94225.81349.52631.590
P<0.001<0.001<0.001<0.001
表5 3组病情相关因子对比(mean±SD)
时间组别例数Cor(nmol/L)ADH(pg/mL)胃泌素(pg/mL)血红蛋白(g/L)
治疗前A组44318.45±34.585.74±0.68102.15±23.26101.25±7.98
B组44321.26±35.085.72±0.59105.82±24.10102.06±8.14
C组44319.78±36.125.75±0.69103.54±26.11101.84±9.21
F0.0700.0240.2510.108
P0.9330.9760.7780.898
治疗后A组44242.48±36.08a3.99±0.67a92.76±15.08a106.17±6.92a
B组44219.45±34.59ab3.59±0.75ab84.11±16.23ab108.45±7.52a
C组44186.45±36.48abc2.26±0.72abc75.45±15.98abc109.03±7.10a
F27.34270.78013.2511.948
P<0.001<0.001<0.0010.147
表6 3组血栓弹力图情况对比(mean±SD)
时间组别例数R(min)α(°)MA(mm)
治疗前A组444.08±1.0558.97±8.0353.44±6.59
B组444.09±0.9659.98±7.4554.18±7.03
C组444.06±1.0857.33±7.9853.29±6.84
F0.0101.2860.215
P0.9900.2800.807
治疗后A组444.53±0.89a62.26±6.91a57.14±6.55a
B组444.91±0.82ab67.01±7.02ab60.45±6.81ab
C组445.37±0.93abc70.12±6.89abc64.59±7.01abc
F10.02614.31413.287
P<0.001<0.001<0.001
表7 3组不良反应对比n(%)
组别例数腹胀恶心皮疹呕吐总发生率
A组441(2.27)3(6.82)1(2.27)1(2.27)6(13.64)
B组440(0.00)1(2.27)2(4.55)0(0.00)3(6.82)
C组441(2.27)2(4.55)0(0.00)2(4.55)5(11.36)
χ21.119
P0.572

引文著录: 王苗, 王海英, 黎红光, 金志清, 傅志成, 洪嫣兰. 口服血凝酶及康复新液对急性非静脉曲张性上消化道出血患者止血效果的研究. 世界华人消化杂志 2024; 32(10): 767-773