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©The Author(s) 2018.
世界华人消化杂志. 2018-05-18; 26(14): 834-841
在线出版 2018-05-18. doi: 10.11569/wcjd.v26.i14.834
在线出版 2018-05-18. doi: 10.11569/wcjd.v26.i14.834
分组 | n | EIF3h | χ2 | P | MMP-10 | χ2 | P | MMP-11 | χ2 | P | |||
+ | - | + | - | + | - | ||||||||
观察组 | 110 | 52 (47.3) | 58 (52.7) | 14.581 | 0.000 | 49 (44.5) | 61 (55.5) | 25.048 | 0.000 | 57 (51.8) | 53 (48.2) | 12.025 | 0.001 |
对照组1 | 43 | 15 (34.9) | 28 (65.1) | 11 (25.6) | 32 (74.4) | 9 (20.9) | 34 (79.1) | ||||||
对照组2 | 43 | 6 (14.0) | 37 (86.0) | 10 (23.3) | 33 (76.7) | 8 (18.6) | 35 (81.4) | ||||||
对照组3 | 43 | 2 (4.7) | 41 (95.3) | 1 (2.3) | 42 (97.7) | 3 (7.0) | 40 (93.0) |
临床特征 | n | EIF3h | χ2 | P | MMP-10 | χ2 | P | MMP-11 | χ2 | P | |||
+ | - | + | - | + | - | ||||||||
淋巴结转移 | |||||||||||||
无 | 76 | 28 (36.8) | 48 (63.2) | 10.733 | 0.001 | 28 (36.8) | 48 (63.2) | 5.907 | 0.015 | 34 (44.7) | 42 (55.3) | 4.938 | 0.026 |
有 | 34 | 24 (70.6) | 10 (29.4) | 21 (61.8) | 13 (38.2) | 23 (67.6) | 11 (32.4) | ||||||
分化程度 | |||||||||||||
高-中 | 84 | 32 (38.1) | 52 (61.9) | 12.009 | 0.001 | 39 (46.4) | 45 (53.6) | 0.510 | 0.475 | 45 (53.6) | 39 (46.4) | 0.438 | 0.508 |
低 | 26 | 20 (76.9) | 6 (23.1) | 10 (38.5) | 16 (61.5) | 12 (46.2) | 14 (53.8) | ||||||
最大径 | |||||||||||||
<5 cm | 43 | 10 (23.3) | 33 (76.7) | 16.337 | 0.000 | 19 (44.2) | 24 (55.8) | 0.004 | 0.952 | 27 (62.8) | 16 (37.2) | 3.404 | 0.065 |
≥5 cm | 67 | 42 (62.7) | 25 (37.3) | 30 (44.8) | 37 (55.2) | 30 (44.8) | 37 (55.2) | ||||||
脉管侵犯 | |||||||||||||
无 | 88 | 42 (47.7) | 46 (52.3) | 0.036 | 0.849 | 34 (38.6) | 54 (61.4) | 9.219 | 0.013 | 41 (46.6) | 47 (53.4) | 4.815 | 0.028 |
有 | 22 | 10 (45.5) | 12 (54.5) | 15 (68.2) | 7 (31.8) | 16 (72.7) | 6 (27.3) | ||||||
性别 | |||||||||||||
男 | 57 | 22 (38.6) | 35 (61.4) | 3.573 | 0.059 | 26 (45.6) | 31 (54.4) | 0.055 | 0.815 | 29 (50.9) | 28 (49.1) | 0.042 | 0.838 |
女 | 53 | 30 (56.6) | 23 (43.4) | 23 (43.4) | 30 (56.6) | 28 (52.8) | 25 (47.2) | ||||||
年龄 | |||||||||||||
<60 | 40 | 22 (55.0) | 18 (45.0) | 1.506 | 0.220 | 14 (35.0) | 26 (65.0) | 2.319 | 0.128 | 25 (62.5) | 15 (37.5) | 2.873 | 0.090 |
≥60 | 70 | 30 (42.9) | 40 (57.1) | 35 (50.0) | 35 (50.0) | 32 (45.7) | 38 (54.3) | ||||||
炎细胞浸润 | |||||||||||||
轻 | 64 | 27 (42.2) | 37 (57.8) | 1.588 | 0.208 | 29 (45.3) | 35 (54.7) | 0.036 | 0.849 | 36 (56.3) | 28 (43.8) | 1.204 | 0.273 |
重 | 46 | 25 (54.3) | 21 (45.7) | 20 (43.5) | 26 (56.5) | 21 (45.7) | 25 (54.3) | ||||||
增殖指数 | |||||||||||||
<50% | 43 | 14 (32.6) | 29 (7.4) | 6.491 | 0.011 | 19 (44.2) | 24 (55.8) | 0.004 | 0.952 | 25 (58.1) | 18 (41.9) | 1.130 | 0.288 |
≥50% | 67 | 38 (57.4) | 29 (42.6) | 30 (44.8) | 37 (55.2) | 32 (47.8) | 35 (52.2) | ||||||
TNM分期 | |||||||||||||
Ⅰ+Ⅱ期 | 81 | 32 (39.5) | 49 (60.5) | 7.435 | 0.006 | 33 (40.7) | 48 (59.3) | 1.800 | 0.180 | 40 (49.4) | 41 (50.6) | 0.730 | 0.393 |
Ⅲ+Ⅳ期 | 29 | 20 (69.0) | 9 (31.0) | 16 (55.2) | 13 (44.8) | 17 (58.6) | 12 (41.4) |
引文著录: 沈渊, 沈瑛, 刘江, 施杰民, 丁建. EIF3h、MMP-10和MMP-11在结肠腺癌中的表达及意义. 世界华人消化杂志 2018; 26(14): 834-841