Copyright
©The Author(s) 2015.
世界华人消化杂志. 2015-09-08; 23(25): 4094-4100
在线出版 2015-09-08. doi: 10.11569/wcjd.v23.i25.4094
在线出版 2015-09-08. doi: 10.11569/wcjd.v23.i25.4094
表1 两组患者一般情况的比较
| 因素 | 对照组(n = 202) | NAFLD(n = 198) | χ2值 | P值 |
| 吸烟 | 1.190 | 0.275 | ||
| 有 | 112 | 99 | ||
| 无 | 90 | 99 | ||
| 吸烟>20支/d | 2.543 | 0.111 | ||
| 有 | 112 | 94 | ||
| 无 | 90 | 104 | ||
| 脂肪肝 | 2.337 | 0.126 | ||
| 有 | 144 | 127 | ||
| 无 | 58 | 71 | ||
| 高脂肪饮食 | 26.938 | 0.000 | ||
| 有 | 106 | 153 | ||
| 无 | 96 | 45 | ||
| 冠心病 | 0.360 | 0.548 | ||
| 有 | 104 | 96 | ||
| 无 | 98 | 102 | ||
| 糖尿病 | 2.864 | 0.091 | ||
| 有 | 128 | 109 | ||
| 无 | 74 | 89 |
表2 汉族和维吾尔族患者人体学及生物化学指标比较 (mean±SD)
| 因素 | 汉族 | t值 | P值 | 维吾尔族 | t值 | P值 | ||
| 对照组 | NAFLD组 | 对照组 | NAFLD组 | |||||
| 身高(cm) | 167.0600±8.6880 | 167.0800±8.45400 | -0.014 | 0.988 | 164.5500±6.59600 | 163.1200±7.96700 | 1.064 | 0.289 |
| 体质量(kg) | 78.8100±8.3420 | 76.2900±11.03700 | 1.480 | 0.141 | 71.7200±10.12700 | 83.5400±12.98000 | -5.454 | 0.000 |
| BMI(kg/m2) | 28.3940±3.6880 | 27.1930±3.04500 | 2.188 | 0.030 | 23.4310±3.03100 | 31.2210±4.74300 | -6.298 | 0.000 |
| 腰臀比 | 0.8110±0.0710 | 1.3030±0.22068 | -15.934 | 0.000 | 0.9187±0.07985 | 1.3125±0.22732 | -11.506 | 0.000 |
| 收缩压(mmHg) | 121.5900±10.7590 | 145.0100±22.03600 | -7.363 | 0.000 | 122.8100±13.42200 | 152.0400±21.93500 | -8.371 | 0.000 |
| 舒张压(mmHg) | 75.3900±7.1360 | 81.6200±15.14600 | -2.861 | 0.005 | 76.9400±9.72800 | 90.1700±15.61900 | -5.307 | 0.000 |
| 空腹血糖(mmol/L) | 5.1760±0.5432 | 5.9740±2.98410 | -1.946 | 0.053 | 4.7430±0.52320 | 7.6070±3.30390 | -5.895 | 0.000 |
| BUN(mmol/L) | 4.3310±2.2956 | 5.9850±3.42790 | -3.193 | 0.002 | 4.7520±2.20380 | 8.7600±2.06000 | -10.617 | 0.000 |
| Cr(mmol/L) | 80.0600±23.9750 | 63.8700±31.07700 | 3.348 | 0.001 | 80.7400±25.75400 | 77.0000±32.09100 | 0.695 | 0.488 |
| CRP(mg/L) | 4.4270±0.7645 | 10.1140±11.76940 | -3.542 | 0.001 | 4.0110±1.37320 | 12.0400±9.31980 | -5.863 | 0.000 |
| TC(mmol/L) | 4.4530±0.7761 | 5.1835±1.34800 | -3.678 | 0.000 | 4.0072±0.91300 | 7.2048±1.24700 | -15.870 | 0.000 |
| TG(mmol/L) | 0.9980±2.5980 | 2.5979±1.62100 | -7.079 | 0.000 | 0.9900±0.37400 | 7.5190±1.53700 | -25.654 | 0.000 |
表3 NAFLD组和对照组指标比较 (mean±SD)
| 因素 | 非NAFLD(n = 202) | NAFLD(n = 198) | t值 | P值 |
| 身高(cm) | 165.891±7.829 | 165.217±8.444 | 0.828 | 0.408 |
| 体质量(kg) | 75.515±9.809 | 79.692±12.496 | 3.714 | 0.000 |
| BMI(kg/m2) | 27.481±3.513 | 29.085±4.412 | 4.019 | 0.000 |
| 腰围(cm) | 86.289±5.747 | 98.778±16.242 | 10.211 | 0.000 |
| 臀围(cm) | 83.540±8.560 | 76.280±9.332 | 8.110 | 0.000 |
| 腰臀比 | 1.161±0.092 | 1.270±0.187 | 7.366 | 0.000 |
| 收缩压(mmHg) | 122.158±11.995 | 148.313±22.213 | 14.611 | 0.000 |
| 舒张压(mmHg) | 76.109±8.412 | 85.636±15.917 | 7.463 | 0.000 |
| 空腹血糖(mmol/L) | 4.974±0.572 | 6.741±3.235 | 7.568 | 0.000 |
| UA(μmol/L) | 302.188±67.139 | 294.110±94.855 | 0.981 | 0.325 |
| BUN(mmol/L) | 4.527±2.246 | 7.288±3.180 | 10.011 | 0.000 |
| Cr(mmol/L) | 80.376±24.634 | 70.033±32.155 | 3.606 | 0.005 |
| CRP(mg/L) | 4.233±1.102 | 11.019±10.706 | 8.872 | 0.000 |
| TC(mmol/L) | 0.994±0.435 | 4.910±2.925 | 18.635 | 0.000 |
| TG(mmol/L) | 4.246±0.865 | 6.133±1.646 | 14.315 | 0.000 |
表4 NAFLD组和对照组多因素分析
| 因素 | B | S.E. | Wald | P值 | OR | 95%CI for OR | |
| 下限 | 上限 | ||||||
| 收缩压 | 0.069 | 0.016 | 17.320 | 0.000 | 1.071 | 1.037 | 1.106 |
| BUN | 0.362 | 0.130 | 7.775 | 0.005 | 1.436 | 1.114 | 1.852 |
| Cr | -0.044 | 0.012 | 13.113 | 0.000 | 0.957 | 0.934 | 0.980 |
| CRP | 0.203 | 0.075 | 7.431 | 0.006 | 1.226 | 1.059 | 1.419 |
| TG | 2.525 | 0.465 | 29.510 | 0.000 | 12.486 | 5.021 | 31.046 |
引文著录: 梁灿灿, 丁永年, 纪文静, 石洁, 叶尔奴尔. 乌鲁木齐市维吾尔族非酒精性脂肪性肝病危险因素的评估. 世界华人消化杂志 2015; 23(25): 4094-4100