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©The Author(s) 2009.
世界华人消化杂志. 2009-01-28; 17(3): 273-278
在线出版 2009-01-28. doi: 10.11569/wcjd.v17.i3.273
在线出版 2009-01-28. doi: 10.11569/wcjd.v17.i3.273
分组 | n | 基因型 | |||
BB | Bb | bb | BB+Bb | ||
病例组 | 50 | 4(8.0) | 6(12.0) | 40(80.0) | 10(10.0) |
对照组 | 72 | 19(26.4) | 10(13.9) | 43(59.7) | 29(40.3) |
合计 | 122 | 23(18.9) | 16(13.1) | 83(68.0) | 39(32.0) |
OR | 31.667 | 1.550 | 2.698 | 0.371 | |
95% CI | 7.983-125.618 | 0.516-4.657 | 1.167-6.235 | 0.160-0.857 | |
P | 0.028 | 0.001 | 0.435 | 0.020 | 0.018 |
分组 | 等位基因 | OR | 95% CI | Pearson列联系数 | |
b | B | ||||
病例组 | 86(86.0) | 14(14.0) | |||
对照组 | 96(66.7) | 48(33.3) | 3.071 | 1.583-3.958 | 0.213 |
合计 | 182(74.6) | 72(25.4) |
研究因素 | 变量 | 赋值 |
年龄(岁) | X1 | <45 = 1, 45-54 = 2, 55-64 = 3, >65 = 4 |
性别 | X2 | 女 = 0, 男 = 1 |
饮酒状况 | X3 | 不饮酒 = 0, 饮酒 = 1 |
基因型 | X4 | Bb = 0, BB = 1, bb = 2 |
ALT | X5 | <50 U/L = 0, >50 U/L = 1 |
AST | X6 | <50 U/L = 0, >50 U/L = 1 |
ALT/AST | X7 | <1 = 0, >1 = 1 |
总胆红素 | X8 | 3.4-17.1 μmol/L = 0, >17.1 μmol/L = 1 |
结合胆红素 | X9 | 0-6.8 μmol/L = 0, >6.8 μmol/L = 1 |
非结合胆红素 | X10 | 1.7-17.1 μmol/L = 0, >17.1 μmol/L = 1, |
CHOL | X11 | 3.60-5.70 mmol/L = 0, >5.70 mmol/L = 1 |
TG | X12 | 0.80-1.80 mmol/L = 0, >1.80 mmol/L = 1 |
HDL | X13 | 0.80-1.08 mmol/L = 0, >1.08 mmol/L = 1 |
LDL | X14 | 1.55-3.70 mmol/L = 0, >3.70 mmol/L = 1 |
透明质酸(HA) | X15 | 50.0-120.0 mg/L = 0, >120.0 mg/L = 1 |
层黏蛋白(LN) | X16 | 90.0-133.0 μg/L = 0, >133.0 μg/L = 1 |
人型前胶原(HacⅢ) | X17 | <120.0 μg/L = 0, >120.0 μg/L = 1 |
Ⅳ型胶原(Ⅳ.C) | X18 | <84.7 μg/mL = 0, >84.7 μg/mL = 1 |
结合胆酸(SCG) | X19 | <290.0 μg/mL = 0, >290.0 μg/mL = 1 |
是否患酒精性肝病 | Y | 对照 = 0, 患者 = 1 |
入选变量 | 回归系数b | 标准误Sb | WaldΧ2 | P | OR | 95% CI For OR | |
Lower | Upper | ||||||
X3 | 9.613 | 29.010 | 0.110 | 0.740 | 14964.120 | 0.000 | 7.4E+28 |
X4 | 0.821 | 0.434 | 3.580 | 0.058 | 2.272 | 0.971 | 5.318 |
X5 | 3.649 | 1.085 | 11.319 | 0.001 | 38.439 | 4.587 | 322.120 |
常数项 | -11.487 | 29.018 | 0.157 | 0.692 | 0.000 |
引文著录: 孙平, 王沁. 维生素D受体基因多态性与酒精性肝病的相关性. 世界华人消化杂志 2009; 17(3): 273-278