中国检验幽门螺杆菌感染方法诊断效能的分析

表1 H. pylori培养试验之相关文献及统计数字

序号i	H. pylori				合计	Se(%)	Sp(%)	p(%)	PV(+)(%)	PV(-)(%)
	+		-
	A	C	B	D
1[2]	130	42	0	17	189	75.58	100.0	77.78	100.0	28.81
2[3]	30	1	7	53	91	96.77	88.33	91.21	81.08	98.15
3[9]	61	53	8	115	237	53.51	93.50	74.26	88.41	68.45
4[12]	360	40	102	443	945	90.00	81.28	84.97	77.92	91.72
5[15]	47	15	4	34	100	75.81	89.47	81.00	92.16	69.39
6[17]	175	26	0	58	259	87.06	100.0	89.96	100.0	69.05
7[31]	41	2	0	33	76	95.35	100.0	97.37	100.0	94.29
8[32]	264	107	3	221	485	71.16	98.66	100.0	98.88	67.38
9[35]	40	39	0	16	95	50.63	100.0	58.95	100.0	29.09
10[51]	60	8	0	27	95	88.24	100.0	91.58	100.0	77.14
合计	1208	333	124	1017	2572	78.39	89.13	86.51	90.69	75.33

表2 快速尿素酶诊断试验之相关文献及统计数字

序号 i	H. pylori				合计	Se(%)	Sp(%)	p(%)	PV(+)(%)	PV(-)(%)
	+		-
	A	C	B	D
1[2]	151	15	18	90	274	90.96	83.33	87.96	89.35	85.71
2[4]	49	4	4	33	90	92.45	89.19	91.11	92.45	89.19
3[5]	80	7	9	21	117	91.95	70.00	86.32	89.89	75.00
4[6]	48	4	2	14	68	92.31	87.50	91.18	96.00	77.78
5[7]	130	12	4	40	186	91.55	90.91	91.40	97.01	76.92
6[8]	59	2	3	82	146	96.72	96.47	96.58	95.16	97.62
7[9]	50	3	4	41	98	94.34	91.11	92.86	92.59	93.18
8[20]	42	11	11	36	100	79.25	76.60	78.00	79.25	76.60
9[21]	45	1	3	33	82	97.83	91.67	95.12	93.75	97.06
10[22]	45	8	2	10	65	84.91	83.33	84.62	95.74	55.56
11[24]	33	11	1	12	57	75.00	92.31	78.95	97.06	52.17
12[25]	81	15	6	58	160	84.38	90.63	86.88	93.10	79.45
13[29]	53	4	3	20	80	92.98	86.96	91.25	94.64	83.33
14[30]	31	1	2	53	87	96.88	96.36	96.55	93.94	98.15
15[31]	151	50	0	58	259	75.12	100.0	80.69	100.0	53.70
16[32]	41	2	0	33	76	95.35	100.0	97.37	100.0	94.29
17[37]	62	3	5	13	83	95.38	72.22	90.36	92.54	81.25
18[39]	55	4	7	53	119	93.22	88.33	90.76	88.71	92.98
19[42]	36	3	3	20	62	92.31	86.96	90.32	92.31	86.96
20[43]	79	9	3	35	126	89.77	92.11	90.48	96.34	79.55
21[44]	228	31	3	98	360	88.03	97.03	90.56	98.70	75.97
22[45]	44	8	4	34	90	84.62	89.47	86.67	91.67	80.95
23[46]	119	12	5	49	185	90.84	90.74	90.81	95.97	80.33
24[48]	71	23	25	61	180	75.53	70.93	73.33	73.96	72.62
25[49]	64	15	3	13	95	81.01	81.25	81.05	95.52	46.43
26[51]	65	3	1	26	95	95.59	96.30	95.79	98.48	89.66
27[53]	241	29	10	104	384	89.26	91.23	89.8	96.02	78.20
28[54]	61	8	0	31	100	88.41	100.0	92.00	100.0	79.49
29[55]	46	6	4	12	70	88.46	75.00	82.86	92.00	66.67
合计	2260	304	145	1183	3894	88.14	89.08	88.42	93.97	79.56

表3 不同诊断方法综合评价结果比较[57]

序号	论文数量	诊断方法	Se(%)	Sp(%)	p(%)	PV(+)(%)	PV(-)(%)
1	10	H. pylori培养试验	78.39	89.13	86.51	90.69	75.33
2	16	病理组织学切片	91.47	93.98	91.89	97.19	82.87
3	13	13C-尿素呼气试验	95.49	94.76	95.53	96.49	93.29
4	15	14C-尿素呼气试验	96.38	90.80	94.34	94.80	93.52
5	10	血清抗H. pylori-IgG	92.04	87.70	98.83	95.08	81.01
6	29	快速尿素酶	88.14	89.08	88.42	93.97	79.56
7	7	胃黏膜涂片镜检	94.53	95.56	96.65	98.36	86.12
8	4	PCR	97.57	89.09	95.44	96.40	92.45
9	10	H. pylori SA	95.57	93.17	94.24	94.23	94.75
10	3	唾液抗H. pylori-IgG	93.06	86.96	91.32	94.71	83.33