三氧化二砷对肝癌诱导血管内皮细胞相关基因蛋白表达的影响

表1 三氧化二砷对ECV304细胞肿瘤相关基因表达的影响(mean±SD, n = 6)

	VEGF	EGFR	CD-29	E-CD
对照组	123.17±23.67	126.67±16.82	102.67±25.90	13.33±5.501
用药组	9.5±5.4	9.5±5.89	9±6.19	103±18.58
ｔ	11.466	16.10	8.614	11.335
P	<0.01	<0.01	<0.01	<0.01

表2 三氧化二砷对SMMC-7721细胞肿瘤相关基因表达的影响(mean±SD, n = 6)

	VEGF	EGFR	CD-29	E-CD
对照组	75.83±27.61	106±27.80	108.67±33.74	15±8.56
用药组	10.83±6.15	19.33±14.83	14.5±8.85	107.5±21.51
ｔ	5.629	6.738	6.613	9.788
P	<0.01	<0.01	<0.01	<0.01

表3 三氧化二砷对肝癌细胞条件液培养的ECV304细胞肿瘤相关基因表达的影响(mean±SD, n = 6)

	VEGF	EGFR	CD-29	E-CD
对照组	131.67±25.16	142.83±15.13	99.83±21.78	17.33±9.87
用药组	21.83±7.63	9.33±4.18	9.67±5.89	98.67±18.86
ｔ	10.233	20.831	9.787	9.357
P	<0.01	<0.01	<0.01	<0.01