口咽胃肠道环境对Der p2-rBCG行为的影响

表1 不同时间粪便中BCG计数(× 10⁴CFU)

Day	BCG	Der p2-rBCG
		SEC	CW	IC
1	2.36±0.78	3.15±1.32	2.67±0.83	4.03±1.56
6	511.33±131.25	752.41±237.34	681.53±178.43	558.76±145.91
8	37.23±27.95	1.61±42.15	79.13±55.59	77.44±37.53
10	6.66±5.89	7.97±6.05	8.63±5.72	5.51±5.38
14	0	0	0	0
28	0	0	0	0
56	0	0	0	0

表2 不同组织中BCG计数(×10⁴CFU)

		OLT	GALT	Lung	Spleen	Liver
BCG	2	10.35±3.01	9.52±2.13	4.76±1.38	8.07±2.19	3.58±0.77
	14	74.25±8.75	85.39±14.76	63.45±8.59	95.86±15.73	43.18±5.43
	28	32.12±6.33	29.54±9.36	5.85±2.39	42.49±10.27	12.34±4.26
	56	0	0	0	0	0
rBCG-SEC	2	13.26±2.43	8.87±1.95	6.48±1.92	11.23±3.53	5.77±1.12
	14	94.16±12.35	71.67±11.22	49.37±6.58	93.46±10.13	53.39±9.84
	28	26.92±4.65	33.23±8.19	8.35±3.27	34.91±8.94	10.16±3.75
	56	0	0	0	0	0
rBCG-CW	2	8.52±2.84	10.36±2.17	7.35±2.61	9.42±3.13	5.93±1.09
	14	76.18±9.64	83.57±11.63	57.39±6.95	86.49±11.92	46.34±4.53
	28	36.65±8.74	28.18±7.83	9.69±3.12	44.67±13.85	9.64±3.78
	56	0	0	0	0	0
rBCG-IC	2	6.95±2.67	7.56±1.43	5.15±1.62	6.56±1.38	5.18±1.07
	14	73.16±8.37	81.66±10.34	54.39±6.26	81.32±12.62	47.52±4.61
	28	26.25±4.83	25.44±6.51	7.68±2.42	37.33±9.18	10.54±3.16
	56	0	0	0	0	0