针对端粒酶蛋白催化亚单位的肿瘤免疫治疗研究

表1 源于hTERT的T淋巴细胞表位

表位	氨基酸序列	HLA限制性单元	MHC类别
I 540[89]	ILAKFLHWL	HLA-A2	MHC-I
R572[89]	RLFFYRKSV	HLA-A2	MHC-I
D988[89]	DLQVNSLQTV	HLA-A2	MHC-I
K973[92]	KLFGVLRLK	HLA-A3	MHC-I
V324[93]	VYAETKHFL	HLA-A24	MHC-I
V461[93]	VYGFVRACL	HLA-A24	MHC-I
hTERT(766)[94]	LTDLQPYMRQFVAHL	HLA-DR4, DR11, and DR15	MHC-II
hTERT(672)[94-95]	RPGLLGASVLGLDDI	HLA-DR1, DR7, and DR15	MHC-II