胃癌耐药相关抗体MGr1筛选文库获得的基因MGr1-Ag1在胃癌组织中表达的研究

表1 在胃癌、癌旁组织和正常胃黏膜中的表达

Group	№	MGr1-Ag1				T	R(%)
		-	+	++	+++
GC	42	21	9	10	2	21	50.00
PC	42	12	12	15	3	30	71.42
NT	25	8	5	9	3	17	68.00

NT: nomal gastric tissue; GC: gastric cancer; PC: paracancerous gastric mucosa; Pearson Chi-Square Tests: x² = 4.043; df = 1; P = 0.044<0.05; GC vs PC.

表2 MGr1-Ag1 mRNA的表达和胃癌分型

Group	№	Grade of intensity				T	R(%)
		-	+	++	+++
WD	16	5	5	5	1	11	68.75
MD	14	6	3	4	1	8	57.14
PD	10	9	1	0	0	1	10.00
MC	2	1	0	1	0	1	50.00

MC: mucous carcinoma including mucous adenocarcinoma and signet ring cell carcinoma; WD: well differentiated adenocarcinomas; MD: moderately differentiated adenocarcinoma; PD: poorly differentiated adenocarcinoma; Fisher's Exact Test: P = 0.005<0.05 WD vs PD; P = 0.033<0.05 MD vs PD.