胃癌耐药细胞株OCUM-2M/VP16的建立及其耐药机制

图1 OCUM-2M及OCUM-2M/VP16细胞生长曲线. 曲线代表3次实验数据平均值及标准差. ^aP<0.05, ^bP<0.01 vs OCUM-2M/VP16.

图2 OCUM-2M及OCUM-2M/VP16周期流式图. A: OCUM-2M; B: OCUM-2M/VP16.

图3 OCUM-2M及OCUM-2M/VP16基因mRNA表达. 各基因左边条带为OCUM-2M, 右边为OCUM-2M/VP16. Marker: 50-ladder.

图4 OCUM-2M及OCUM-2M/VP16基因灰度比较. 1: GAPDH; 2: caspase-3; 3: P53; 4: DAPK-1; 5: DAPK-2; 6: DAPK-3; 7: Bcl-2; 8: ERCC-1; 9: MRP; 10: MDR-1; ^aP<0.05 vs OCUM-2M.