Expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor and its intervention by interleukin-10 in experimental hepatic fibrosis

Table 1 Intensities for IGF-1/IGF-1R immunoreactivities in groups C, M and T

Group	n	IGF-1				IGF-1R
		-	+	++	Ridit value	-	+	++	Ridit value
C	21	13	8	0	0.302acf	14	7	0	0.331ac
M	25	2	10	13	0.689acd	5	8	12	0.666ace
T	28	8	16	4	0.480adf	10	16	2	0.478ae

^aP < 0.01 vs among three groups,

^cP < 0.01 group M vs group C

^dP < 0.01,

^eP < 0.05 group M vs group T,

^fP < 0.05 group C vsgroup T.

Table 2 Intensities for IGF-1 and IGF-1R immunoreactivities in different time points of hepatic fibrosis induced by CCl₄

Week	n	IGF-1				IGF-1R
		-	+	++	Ridit value	-	+	++	Ridit value
5 wk	8	0	1	7	0.683ab	0	1	7	0.710ab
7 wk	8	0	4	4	0.510a	2	3	3	0.445a
9 wk	9	2	5	2	0.329ab	3	4	2	0.362ab

^aP < 0.05 vs among three groups,

^bP < 0.05, 5 wk vs 9 wk.

Table 3 Intensities for IGF-1 and IGF-1R immunoreactivities in different periods of hepatic fibrosis in group T

Week	n	IGF-1				IGF-1R
		-	+	++	idit value	-	+	++	idit value
5 wk	10	0	7	3	0.678ab	1	7	2	0.661ab
7 wk	9	3	5	1	0.468ab	3	6	0	0.488a
9 wk	9	5	4	0	0.333ab	6	3	0	0.334ab

^aP < 0.05 vs among three groups,

^bP < 0.05, 5 wk vs 9 wk.