TT virus infection in patients with chronic hepatitis B and response of TTV to lamivudine

Table 1 Comparison of serum TTV DNA concentration changes before treatment and at the end of treatment

	Non-responders (n = 7)	Responders (n = 8)	Pa
Before treatment	4.6 × 107	8.0 × 107	0.66
End of treatment	1.1 × 108	3.4 × 107	0.29

TTV DNA concentration was expressed as viral genomes/mL of serum. ^aStudent's t-test, HBV non-responsive patients vs. responsive patients to lamivudine therapy.

Table 2 Changes of TTV DNA concentration in HBV non-responsive and responsive patients to lamivudine therapy

	Before treatment	End of treatment	Pa
Non-responders (n = 7)	4.6 × 107	1.1 × 108	0.60
Responders (n = 8)	8.0 × 107	3.4 × 107	0.55

TTV DNA concentration was expressed as viral genomes/mL of serum. ^aStudent's t-test, before vs at the end of treatment.

Table 3 Comparison of serum TTV DNA concentration changes before treatment and at the end of treatment

	Non-transplanted (n = 5)	Transplanted (n = 10)	Pa
Before treatment	1.2 × 107	8.9 × 107	0.22
End of treatment	8.8 × 106	1.0 × 108	0.07

TTV DNA concentration was expressed as viral genomes/mL of serum. ^aStudent's t-test, non-transplanted vs. transplanted patients.

Table 4 Changes in TTV DNA concentration in non-transplanted and transplanted patients

	Before treatment	End of treatment	Pa
Non-transplanted (n = 5)	1.2 × 107	8.8 × 106	0.59
Transplanted (n = 10)	8.9 × 107	1.0 × 108	0.87

TTV DNA concentration was expressed as viral genomes/mL of serum. ^aStudent's t-test, before vs at the end of treatment.