Crohn’s disease and risk of fracture: does thyroid disease play a role?

Table 1 Comparison of baseline characteristics and thyroid status in patients with Crohn’s disease and control group

	Case (n = 210)	Control (n = 206)	P
Age (years)	49.24 ± 13.71	48.58 ± 18.43	0.68
Sex (M/F)	88/122	91/113	0.29
Body Mass Index (kg/cm2)	24.35	27.46	0.001
Race (white/black/others)	153/1/34	118/14/36	0.34
Steroid use	75 (35.7%)	None	_
Immunosuppressive therapy	22 (10.4%)	None	_
Hypothyroidism	8 (3.8%)	17 (8.2%)	0.05
Hyperthyroidism	2 (0.01%)	None	0.25

Table 2 Comparison of medical and surgical treatment in pa-tients with hypothyroidism and euthyroidism in Crohn’s disease

	Hypothyroidism (n = 8)	Euthyroid (n = 201)	P
Immunosuppresive medications	None	22 (11%)	0.59
Steroid use	1 (12.5%)	74 (37%)	0.15
Small bowel surgery	1 (12.5%)	56 (28%)	0.34
Large bowel surgery	1 (12.5%)	54 (27%)	0.38