Sheen IS, Jeng KS, Tsai YC. Is the expression of γ-glutamyl transpeptidase messenger RNA an indicator of biological behavior in recurrent hepatocellular carcinoma? World J Gastroenterol 2003; 9(3): 468-473 [PMID: 12632499 DOI: 10.3748/wjg.v9.i3.468]
Corresponding Author of This Article
Kuo-Shyang Jeng, M.D., F.A.C.S.Department of Surgery, Mackay Memorial Hospital, No. 92, Sec 2, Chung-San North Road, Taipei, Taiwan, China. issheen.jks@msa.hinet.net
Article-Type of This Article
Liver Cancer
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Table 7 Significant factors in recurrence and death
Parameters
Recurrence
Death
UV
MV
UV
MV
Sex
n.s.
n.s.
n.s.
n.s.
Age
n.s.
n.s.
n.s.
n.s.
Child-Pugh’s classification: A vs. B
n.s.
n.s.
n.s.
n.s.
HBsAg (+)
n.s.
n.s.
0.0166
n.s.
HCV (+)
n.s.
n.s.
n.s.
n.s.
AFP < 20 vs. 20-1000
0.0001
0.0108
0.0006
0.0141
γ-GTP mRNA (+)
n.s.
n.s.
n.s.
n.s.
Pathology of HCC:
Size: <3 cm vs. 3-10 cm
0.0213
n.s.
0.0080
n.s.
Cirrhosis
n.s.
n.s.
n.s.
n.s.
Edmondson-Steiner grade
0.0001
n.s.
0.0007
n.s.
Complete capsule (+)
< 0.0001
0.0084
< 0.0001
0.0130
Vascular permeation (+)
0.0003
n.s.
0.0001
0.0053
Daughter nodules (+)
0.0549
n.s.
0.0550
n.s.
Multicentric (+)
0.0094
n.s.
0.0119
n.s.
Type B γ-GTP mRNA in HCC liver
0.0003
0.0107
0.0046
n.s.
Type B γ-GTP mRNA in non-HCC liver
0.0001
n.s.
0.0007
n.s.
Citation: Sheen IS, Jeng KS, Tsai YC. Is the expression of γ-glutamyl transpeptidase messenger RNA an indicator of biological behavior in recurrent hepatocellular carcinoma? World J Gastroenterol 2003; 9(3): 468-473