Role of oxygen free radicals in patients with acute pancreatitis

Table 1 Laboratory parameters in patients with acute pancre-atitis and control group

Parameters	Control (n = 14)	Acute pancreatitis (n = 13)	Pvalue
Amylase (IU/dL)	141.9 ± 179.3	393.3 ± 243.1	0.005
LPO (nmol/mL)	5.7 ± 1.7	21.9 ± 26.5	0.030
MPO (nmol/mL)	2.7 ± 1.2	12.3 ± 11.7	0.005
SOD (U/dL)	100.4 ± 20.2	48.2 ± 41.4	0.002

Values are means ± SD, LPO = lipid peroxide, MPO = myeloperoxidase, SOD = superoxide dismutase.

Table 2 Laboratory parameters according to etiology of acute pancreatitis

Paramerters	Gallstone group (n = 5)	Alcohol group (n = 4)	Pvalue
Age (years)	55.4 ± 19.7	44.5 ± 14.2	0.368
Amylase (IU/dL)	364.6 ± 271.9	366.5 ± 252.5	0.992
Lipase (IU/dL)	10004.0 ± 15873.2	6035.8 ± 8265.2	0.646
CRP (mg/dL)	6.0 ± 2.5	12.3 ± 9.8	0.296
LPO (nmol/mL)	15.6 ± 10.5	38.7 ± 45.1	0.385
MPO (nmol/mL)	11.3 ± 15.3	15.5 ± 14.3	0.689
SOD (U/dL)	59.2 ± 49.3	21.0 ± 17.1	0.171

Values are means ± SD, LPO = lipid peroxide, MPO = myeloperoxidase, SOD = superoxide dismutase.

Table 3 Clinical characteristics of patients with acute pancre-atitis classified according to Atlanta classification

	Mild group	Severe group
No. of cases	8	5
Age (years)	53.5 ± 17.1	53.8 ± 15.7
Sex (M:F)	7:1	5:1
Etiology
Gallstone	2	3
Alcohol	2	2
Others*	4	0
No. of mortality	0	0

^*One case was due to hyperlipidemia and 3 cases were idiopathic.

Table 4 Laboratory parameters in patients with mild and se-vere pancreatitis according to Atlanta classification

Parameters	Mild group (n = 8)	Severe group (n = 5)	Pvalue
Amylase (IU/dL)	374.7 ± 252.4	423.0 ± 253.1	0.745
Lipase (IU/dL)	10082.8 ± 12565.6	30008.0 ± 3314.9	0.167
CRP (mg/dL)	6.7 ± 4.5	12.3 ± 9.0	0.311
LPO (nmol/mL)	11.5 ± 6.8	38.7 ± 38.1	0.068
MPO (nmol/mL)	7.5 ± 4.1	20.1 ± 15.4	0.053
SOD (U/dL)	65.7 ± 49.2	27.3 ± 15.4	0.130
Ranson’s score	1.4 ± 0.7	2.8 ± 1.9	0.177
CT severity index	2.0 ± 1.1	5.8 ± 3.1	0.008

Values are means ± SD, LPO = lipid peroxide, MPO = myeloperoxidase, SOD = superoxide dismutase.