Copyright
©The Author(s) 2003.
World J Gastroenterol. Jan 15, 2003; 9(1): 16-21
Published online Jan 15, 2003. doi: 10.3748/wjg.v9.i1.16
Published online Jan 15, 2003. doi: 10.3748/wjg.v9.i1.16
Table 1 Expression of P53 protein in 25 CC patients
Number | Sex/age | P53 immunostaining | |||
SCC | GCA | ||||
(+/-)a | Immunostaining pattern | (+/-a) | Immunostaining pattern | ||
001 | M/63 | +a | Diffuse | -a | - |
002 | M/60 | - | - | + | Focus & Scattered |
003 | M/55 | + | Diffuse | - | - |
004 | M/71 | + | Diffuse & Scattered | + | Scattered |
005 | F/56 | + | Scattered & Diffuse | - | - |
006 | M/59 | - | - | - | - |
007 | F/67 | - | - | - | - |
008 | M/62 | + | Diffuse | + | Diffuse |
009 | F/61 | + | Diffuse | - | - |
010 | F/64 | + | Scattered | - | - |
011 | M/65 | + | Diffuse | - | Diffuse |
012 | M/68 | + | Diffuse | - | Diffuse |
013 | M/57 | - | - | - | - |
014 | M/51 | + | Diffuse | - | - |
015 | M/50 | - | - | - | - |
016 | M/67 | + | Scattered | - | Diffuse |
017 | M/70 | + | Focus | - | - |
018 | M/67 | + | Scattered | - | Scattered |
019 | F/74 | - | - | + | Diffuse |
020 | M/49 | - | - | + | Diffuse |
021 | M/36 | - | - | - | - |
022 | M/70 | + | Diffuse | - | - |
023 | F/74 | - | - | - | - |
024 | F/56 | - | - | - | - |
025 | F/38 | + | Scattered | + | Diffuse & Scattered |
Table 2 Expression of PCNA protein in 25 CC patients
Number | Sex/age | PCNA immunostaining | |||
SCC | GCA | ||||
(+/-)a | Immunostaining pattern | (+/-a) | Immunostaining pattern | ||
001 | M/63 | +a | Diffuse | +a | Diffuse |
002 | M/60 | + | Scattered | + | Focus & Scattered |
003 | M/55 | + | Diffuse | + | Diffuse |
004 | M/71 | + | Scattered & Focus | + | Diffuse |
005 | F/56 | + | Scattered & Diffuse | + | Diffuse |
006 | M/59 | + | Scattered & Focus | + | Diffuse |
007 | F/67 | + | Diffuse | + | Focus |
008 | M/62 | + | Diffuse | + | Diffuse |
009 | F/61 | + | Diffuse | + | Diffuse |
010 | F/64 | + | Scattered | + | Diffuse |
011 | M/65 | + | Focus | + | Diffuse |
012 | M/68 | + | Diffuse | + | Diffuse |
013 | M/57 | - | - | - | - |
014 | M/51 | + | Diffuse | - | - |
015 | M/50 | + | Scattered | + | Diffuse |
016 | M/67 | + | Scattered | + | Diffuse |
017 | M/70 | + | Focus | + | Scattered & Focus |
018 | M/67 | + | Diffuse | + | Scattered |
019 | F/74 | + | Diffuse | + | Diffuse |
020 | M/49 | + | Scattered & Focus | + | Diffuse |
021 | M/36 | + | Diffuse | + | Diffuse |
022 | M/70 | - | - | - | - |
023 | F/74 | + | Diffuse | + | Diffuse |
024 | F/56 | + | Scattered & Focus | + | Diffuse |
025 | F/38 | + | Scattered | + | Diffuse |
Table 3 Expression of P53 & PCNA in precancerous lesions of adjacent cancerous tissues
Number of samples | P53 | PCNA | |||
+ | % | - | % | ||
Esophagus | |||||
NOR | 11 | 3 | 27 | 6 | 55 |
BCH | 10 | 5 | 50 | 7 | 70 |
DYS | 8 | 4 | 50 | 6 | 75 |
CIS | 7 | 2 | 29 | 5 | 71 |
SCC | 14 | 10 | 71 | 13 | 93 |
Gastric cardia | |||||
NOR | 9 | 4 | 44 | 6 | 67 |
DYS | 11 | 3 | 27 | 7 | 64 |
CIS | 9 | 2 | 22 | 6 | 67 |
CGA | 14 | 5 | 36 | 12 | 86 |
- Citation: Chen H, Wang LD, Guo M, Gao SG, Guo HQ, Fan ZM, Li JL. Alterations of p53 and PCNA in cancer and adjacent tissues from concurrent carcinomas of the esophagus and gastric cardia in the same patient in Linzhou, a high incidence area for esophageal cancer in northern China. World J Gastroenterol 2003; 9(1): 16-21
- URL: https://www.wjgnet.com/1007-9327/full/v9/i1/16.htm
- DOI: https://dx.doi.org/10.3748/wjg.v9.i1.16