Epidemiological and histopathological study of relevance of Guizhou Maotai liquor and liver diseases

Table 1 Epidemiologic study of the Relationship between Guizhou Maotai liquor and Liver Diseases

	Group	Number	Positive
			Number	Rate (%)
History of liver disease	Maotai Group	99	1	1.0
	Control Group	33	0	0
Symptoms of liver disease	Maotai Group	99	1	1.0
	Control Group	33	0	0
Hepatomegaly	Maotai Group	99	15	15.2
	Control Group	33	3	9.1
Splenomegaly	Maotai Group	99	1	1.0
	Control Group	33	0	0
Abnormal ALT	Maotai Group	99	1	1.0
	Control Group	33	0	0
Reversed A/G	Maotai Group	99	1	1.0
	Control Group	33	0	0
Portal trunk widening	Maotai Group	99	0	0
	Control Group	33	0	0

Table 2 Serum ALT, LN, and HA in Maotai Group (^-x±s)

Group	n	ALT (nkat·L-1)	LN (μg·L-1)	HA (μg·L-1)
Control Group	33	683 ± 150	88 ± 24	106 ± 32
Maotai Group	99	650 ± 100	132 ± 71a	293 ± 194a

^aP < 0.05, vs control group

Table 3 The effect of Maotai wine to the liver function of rats (n = 20, ^-x±s)

Group	Serum biochemical index				Liver index and biochemical index
	ALT (nkat·L-1)	AST (nkat·L-1)	Tbil (nmol·L-1)	AKP (nkat·L-1)	Index (g·kg-1)	GSH (mg·g-1)	MDA (A)
Saline	517 ± 233	300 ± 150	12.68 ± 6.47	350 ± 217	27.93 ± 8.64	0.06 ± 0.01	0.66 ± 0.24
Ordinary white wine	567 ± 167	300 ± 67	13.54 ± 2.50	433 ± 67	29.19 ± 4.41	0.08 ± 0.02	0.61 ± 0.22
Maotai wine	533 ± 183	283 ± 133	11.54 ± 6.20	450 ± 133	27.81 ± 2.11	0.12 ± 0.06a	0.33 ± 0.10a

^aP < 0.05, vs control group

Table 4 The effect of Maotai wine to the liver function of mice (n = 20, ^-x±s)

Group	Dosage (mL·kg-1)	ALT (nkat·L-1)	liver index (mg·g-1)	MDA (A)
Saline	10	316 ± 83	40.34 ± 7.54	0.69 ± 0.21
Alcohol	10	333 ± 83	40.96 ± 7.21	0.66 ± 0.32
Maotai wine	10	383 ± 133	43.8 ± 8.79	0.49 ± 0.23a
Maotai wine	20	250 ± 100	39.48 ± 3.84	0.46 ± 0.12a

^aP < 0.05, vs control group