Coinfection of TT virus and response to interferon therapy in patients with chronic hepatitis B or C

Table 1 Demographic data and serum positive percentage of TTV in the two groups

Type	Sex (M/F)	Age (yr)	ALT (IU/L)	TTV DNA
				No. Positive	%
Ba (n = 40)	29/11	33 ± 8c	133 ± 65	6	15
Cb (n = 30)	24/6	41 ± 9	121 ± 60	9	30

^aChronic hepatitis B group.

^bChronic hepatitis C group.

^cP < 0.001.

Table 2 Loss of serum TTV DNA during IFN therapy in the two groups

	Time of IFN Therapy (weeks)						Total
	4	8	12	16	20	24
Ba	3	0	0	0	0	0	3
Cb	6	0	0	0	0	0	6

Data are presented as case number.

^aChronic hepatitis B group.

^bChronic hepatitis C group.

Table 3 Relationship between viral and biochemical responses in the group of chronic hepatitis B

	Virological SR
	HBV (n = 10)	TTV (n = 3)
Biochemical SR (+)	10	1
Biochemical SR (-)	0	2

SR: Sustained response，P = 0.038, by Fisher's exact test

Table 4 Relationship between viral and biochemical responses in the group of chronic hepatitis C

	Virological SR
	HCV (n = 7)	TTV (n = 6)
Biochemical SR (+)	7	2
Biochemical SR (-)	0	4

SR: Sustained response, P = 0.021, by Fisher's exact test