Effects of Yigan Decoction on proliferation and apoptosis of hepatic stellate cells

Table 1 Effects of Yigan Decoction on HSC proliferation (^-x±s)

Groups	Herb concentrations (g·L-1)	ODs	proliferation rates (%)
Yigan Decoction	144	0.08 ± 0.02b	21.62
	72	0.15 ± 0.04b	40.54
	36	0.20 ± 0.03a	54.05
	18	0.17 ± 0.02a	45.95
	9	0.19 ± 0.05a	51.35
	4.5	0.31 ± 0.048	3.78
Control		0.37 ± 0.03	100

^aP < 0.05,

^bP < 0.01 vs control group.

Table 2 Effects of Yigan Decoction on HSC proliferation (× 10⁸·L^-1) (^-x±s)

Groups	24 h	48 h	72 h
Control	1.440 ± 0.124	2.288 ± 0.178	2.335 ± 0.146
Yigan Decoction	1.203 ± 0.112	1.258 ± 0.098b	1.359 ± 0.079b

^bP < 0.01 vs control group.

Table 3 Apoptosis indexes of Yigan Decoction on HSC (^-x±s)

Groups	Herb concentrations (g·L-1)	apoptosis indexes (%)
Yigan Decoction	36	13.3 ± 3.2b
	18	10.7 ± 2.7b
	9	10.1 ± 2.5b
Control		4.1 ± 1.9

^bP < 0.01 vs control group.

Table 4 Time-dependent effects of Yigan Decoction on HSC apoptosis (^-x±s)

Groups	24 h	48 h	72 h
Control	4.5 ± 1.3	7.1 ± 1.9	8.0 ± 1.8
Yigan Decoction	9.3 ± 1.8b	10.7 ± 2.7b	14.6 ± 4.3b

^bP < 0.01 vs control group.