Early diagnosis for colorectal cancer in China

Table 1 The detective rate for early stage of colorectal cancer in China

Authors	Colorectal cancer
	Total n	Early stage n (%)	Year
Lu et al[14]	569	85(15.1)	1997
Ni et al[15]	132	15(11.4)	1997
Yang et al[16]	721	65(22.9)	1997
NI et al[17]	296	32(10.8)	1997
Cai et al[18]	1058	59(5.6)	1999
Zeng et al[19]	300	5(1.7)	1996
Sun et al[20]	180	47(26.1)	1998

Table 2 The malignant transformation rate of polyps in China

Authors	Area	n	Incidence (%)
Zhou et al[22]	Guangzhou	539	3.4
Cai et al[23]	Guangzhou	216	9.7
Zhang et al[24]	Changchun	2000	5.1
Shen et al[25]	Kunming	533	6.4
Zhu et et al[26]	Beijing	219	1.4
Zhu et al[27]	Nanjing	644	5.8
Wang et al[28]	Xi’an	548	9.7
Zhang et al[29]	Zhejiang	321	14.6
Zhang et al[30]	Ha-erbing	494	20.4
Gao et al[31]	Shanghai	334	6.6

Table 3 Morphology of 137 cases of early stage colorectal cancer under endoscopy

Morphology	Type	n	Ratio
Polypoid	I	131	95.6
Elevated	IIa	2	1.4
Flat	IIb	1	0.7
Depressed	IIc or IIc + IIa	3	2.3

Table 4 Histopathology of 186 cases of type II lesion

Morphology	Type	n (%)	Histopathologic diagnosis
			Early cancer	Adenoma	Other
Elevated	IIa	155(83.3)	2(1.3)	86(55.4)	67(43.3)
Flat	IIb	22(11.8)	1(4.5)	2(9.00)	19(86.4)
Depressed	IIc or IIc + IIa	9(4.8)	3(33.3)	4(44.4)	2(22.2)

Table 5 Mass screening for colorectal cancer in asymptomatic population

Authors	Region	Age(yrs)	Population	Cancer	Dukers(%)A/B	Detection rate
Li et al	North	> 35	102800	25	52.0	24/105
Zhen et al	East	> 35	62667	16	57.2	25.5/105
Zhou et al	Mid-south	> 45	24677	9	55.6	36.5/105

Table 6 The follow-up results in 3641 cases of asymtomatic population

	Cancer (n)	Adenoma
		n	> 1.0 cm	Dysplasia( > II grade)
First screen	4	48	17(35.4%)	12(25.0%)
Two years later	0	18	4(22.2%)	2(11.1%)

Table 7 Gene mutation analysis in colorectal cancer stool (Nanfang Hospital)

Gene	n	Tissue DNA		Fecal DNA
		Positive	%	Positive	%
APC	41	20	48.8	14	34.1
MCC	45	13	28.9	11	24.4
P53	32	32	37.5	10	31.3