Study on of bioadhesive property of carbomer934 by a gamma camera in vivo

Table 1 Component proportion of radioactive granules

granules	Percentage/%
	EC	Cb934	Stearic acid
Non-bioadhesive	100	0	0
Bioadheive I	0	100	0
Bioadheive II	0	50	50

Table 2 Non-bioadhesive granules in alimentary tract of dog (n = 3)

Sites	Granules in different segment of alimentary tract(%)
	1 h	2 h	4 h	6 h	8 h	12 h
Stomach	83.7	26.9	7.6	0	0	0
Intestine	16.3	73.2	59.7	0	0	0
Colon	0	0	32.6	43.2	10.6	0

Table 3 Bioadhesive granulesI in alimentary tract of dog (n = 3)

Sites	Granules in different segment of alimentary tract(%)
	1 h	2 h	4 h	6 h	8 h	12 h
Stomach	100	79.6	45.4	23.3	7.5	0
Intestine	20.4	54.7	59.7	55.1	30.9	0
Colon	0	0	0	21.8	61.6	54.3

Table 4 Bioadhesive granules IIin alimentary tract of dog (n = 3)

Sites	Granules in different segment of alimentary tract(%)
	1 h	2 h	4 h	6 h	8 h	12 h
Stomach	100	67.1	37.5	15	0	0
Intestine	0	32.8	51.6	57.9	29.6	0
Colon	0	0	10.9	29.7	70.4	64.8