Relationship between plasma D(-)-lactate and intestinal damage after severe injuries in rats

Table 1 The plasma contents of D(-)-lactate and lipopolysac charide in rats after gut ischemia/reperfusion insults (mean ± SD)

Groups	Time (h)	No. (mmol/L)	D(-)-lactate	LPS (EU/L)
Sham-operated control		10	0.234 ± 0.072	380 ± 84
Gut ischemia	1	10	0.260 ± 0.086	407 ± 41
	1.5	10	0.269 ± 0.092	453 ± 129
Gut ischemia/reperfusion	0.5	10	0.489 ± 0.179b	576 ± 244a
	1	10	0.373 ± 0.179a	611 ± 278a
	2	10	0.253 ± 0.062	562 ± 167a
	6	10	0.237 ± 0.044	335 ± 73
	24	10	0.228 ± 0.025	283 ± 81

Compared with sham-operated control, respectively:

^aP < 0.05;

^bP < 0.01.

Table 2 Changes in systemic blood D(-)-lactate levels and portal blood LPS content in thermal rats (mean ± SD)

Groups	Time (h)	No.	D(-)-lactate (mmol/L)	LPS (EU/L)
Control group		10	0.275 ± 0.175	118 ± 37
Thermal group	3	10	0.371 ± 0.123	159 ± 83
	6	10	0.517 ± 0.162a	347 ± 111a
	12	10	0.619 ± 0.208a	670 ± 139a
	24	10	0.638 ± 0.198a	396 ± 57a

Compared with control group, respectively:

^aP < 0.01.

Table 3 Alterations in systemic blood D(-)-lactate levels and portal blood LPS content in ANP rats (mean ± SD)

Groups	Time (h)	No.	D(-)-lactate (mmol/L)	LPS (EU/L)
Control group		6	0.157 ± 0.044	105 ± 7
ANP group	2	6	0.328 ± 0.063a	301 ± 131a
	8	7	0.507 ± 0.157a	449 ± 164a
	24	7	0.653 ± 0.216a	611 ± 210a
	48	7	0.448 ± 0.112a	422 ± 136a

Compared with control group, respectively:

^aP < 0.01.