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©The Author(s) 2001.
World J Gastroenterol. Aug 15, 2001; 7(4): 506-509
Published online Aug 15, 2001. doi: 10.3748/wjg.v7.i4.506
Published online Aug 15, 2001. doi: 10.3748/wjg.v7.i4.506
Table 1 Main characteristics of cases and controls
Cases (n = 95) | Controls (n = 94) | |||
n | (%) | n | (%) | |
Age groups/yr | ||||
< 50 | 21 | (22.1) | 22 | (23.4) |
50-59 | 23 | (24.2) | 22 | (23.4) |
60-69 | 33 | (34.7) | 34 | (36.2) |
≥ 70 | 18 | (19.0) | 16 | (17.0) |
Mean age | 59 ± 11 | 58 ± 11 | ||
Age range | 32-78 | 34-79 | ||
Gender | ||||
Male | 81 | (85.3) | 82 | (87.2) |
Female | 14 | (14.7) | 12 | (12.8) |
Education | ||||
College | 1 | (1.1) | 1 | (1.1) |
High school | 15 | (15.8) | 63 | (67.0) |
Elementary | 61 | (64.2) | 22 | (23.4) |
school | ||||
Illiterate | 18 | (19.0) | 8 | ( 8.5) |
Table 2 Association between GSTM1 and gastric cancer risk
GSTM1 genotype | ||||||
Nonnull | n | (%) | null | n | (%) | |
Contr | 51 | 54.3 | 43 | 45.7 | ||
Case | 35 | 36.8 | 60 | 63.2 | ||
Crude OR (95%CI) | 2.03 (1.13-3.65) | |||||
Adjusted ORa (95%CI) | 2.03 (1.13-3.68) | |||||
Adjusted ORb (95%CI) | 2.47 (1.21-5.03) | |||||
Adjusted ORc (95%CI) | 2.63 (1.17-5.88) |
Table 3 Association between gastric cancer and combinations of GSTM1 and GSTT1 genotypes
GSTM1 | GSTT1 | Case | Contr | OR (95%CI) | ||
n | % | n | % | |||
Non-null | Non-null | 21 | 22.1 | 30 | 31.9 | 1.00 |
Non-null | Null | 14 | 14.7 | 21 | 22.3 | 0.95 (0.36-2.50) |
Null | Null | 27 | 28.4 | 26 | 27.7 | 1.48 (0.64-3.47) |
Null | Non-null | 33 | 34.7 | 17 | 18.1 | 2.77 (1.15-6.77) |
Table 4 Risk of gastric cancer in relation to GSTM1 genotypes by e smoking
Genotype | Smoke | Contr | Case | OR (95%CI) | ||
n | % | n | % | |||
Nonnull | No | 28 | 29.8 | 12 | 12.6 | 1.00 |
Null | No | 32 | 34.0 | 22 | 23.2 | 1.60 (0.62-4.19) |
Nonnull | Yes | 23 | 24.5 | 23 | 24.2 | 2.33 (0.88-6.28) |
Null | Yes | 11 | 11.7 | 38 | 40.0 | 8.06 (2.83-23.9) |
- Citation: Cai L, Yu SZ, Zhang ZF. Glutathione S-transferases M1, T1 genotypes and the risk of gastric cancer: A case-control study. World J Gastroenterol 2001; 7(4): 506-509
- URL: https://www.wjgnet.com/1007-9327/full/v7/i4/506.htm
- DOI: https://dx.doi.org/10.3748/wjg.v7.i4.506