Copyright
©The Author(s) 2001.
World J Gastroenterol. Feb 15, 2001; 7(1): 33-36
Published online Feb 15, 2001. doi: 10.3748/wjg.v7.i1.33
Published online Feb 15, 2001. doi: 10.3748/wjg.v7.i1.33
Table 1 Expressions of p42/44MAPK, p-Stat3, c-fos and c-jun proteins in HCCs, PCLTs and normal liver tissues
Groups | No | p42/44MAPK | p-Stat3 | c-fos | c-jun | ||||||||||||
- | + | ++ | +++ | - | + | ++ | +++ | - | + | ++ | +++ | - | + | ++ | +++ | ||
Normal | 9 | 9 | 0 | 0 | 0 | 8 | 1 | 0 | 0 | 9 | 0 | 0 | 0 | 9 | 0 | 0 | 0 |
PCLT | 55 | 37 | 9 | 7 | 2 | 42 | 4 | 7 | 2 | 36 | 12 | 7 | 0 | 39 | 13 | 3 | 0 |
HCC | |||||||||||||||||
Grade I | 10 | 1 | 4 | 4 | 1 | 5 | 1 | 2 | 2 | 8 | 1 | 1 | 0 | 4 | 4 | 1 | 1 |
Grade II | 21 | 3 | 6 | 12 | 0 | 2 | 12 | 5 | 2 | 3 | 12 | 4 | 2 | 1 | 15 | 4 | 1 |
Grade III | 17 | 1 | 9 | 2 | 5 | 4 | 3 | 6 | 4 | 2 | 4 | 8 | 3 | 2 | 8 | 5 | 2 |
Grade IV | 7 | 2 | 1 | 3 | 1 | 3 | 1 | 3 | 0 | 0 | 1 | 2 | 4 | 0 | 0 | 2 | 5 |
Table 2 Relationship in expressive strengthes of p42/44MAPK, c-fos and c-jun proteins between HCCs and PCLTs
Groups | r | P |
HCC | ||
p42/44MAPK/c-fos | 0.44835 | < 0.01 |
p42/44MAPK/c-jun | 0.3054 | < 0.01 |
PCLT | ||
p-MAPK/c-fos | 0.9433 | < 0.01 |
p-MAPK/c-jun | 0.1472 | > 0.05 |
Table 3 Relationship in expression strength of p-Stat3, c-fos and c-jun proteins between HCCs and PCLTs
Groups | r | P |
HCC | ||
p-Stat3/c-fos | 0.3967 | < 0.01 |
p-Stat3/c-jun | 0.5444 | < 0.01 |
PCLT | ||
p-Stat3/c-fos | 0.0499 | > 0.05 |
p-MAPK/c-jun | 0.3596 | < 0.01 |
- Citation: Feng DY, Zheng H, Tan Y, Cheng RX. Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance. World J Gastroenterol 2001; 7(1): 33-36
- URL: https://www.wjgnet.com/1007-9327/full/v7/i1/33.htm
- DOI: https://dx.doi.org/10.3748/wjg.v7.i1.33