Expressions of ICAM-1 and its mRNA in sera and tissues of patients with hepatocellular carcinoma

Table 1 Comparative analysis of serum levels of sICAM-1 and AFP in HCC patients

Group	Number of patients	sICAM-1 (μg/L)	AFP (μg/L)
AFP < 20 μg/L	25	1271	18
AFP 20-200 μg/L	33	1456	121
AFP > 200 μg/L	93	1597	26280

Table 2 Clinicopathological analysis of ICAM-1 mRNA and HCC % (n)

Clinical data	Cases	Positive tumor	Positive paratumor
		ICAM-1 mRNA	ICAM-1 mRNA
Serum AFP > 400 μg/L	25	68.0 (17/25)	32.0 (8/25)
Serum AFP < 400 μg/L	18	61.1 (11/18)	27.8 (5/18)
sICAM-1 > 1000 μg/La	32	75.0 (25/32)	34.4 (11/32)
< 1000 μg/L	11	36.4 (3/11)	18.2 (2/11)
Severe cirrhosisa Yes	30	80.0 (24/30)	36.7 (11/30)
No	13	30.8 (4/13)	15.4 (2/13)
Differentiation High	15	66.7 (10/15)	33.3 (4/15)
Low	28	64.3 (18/28)	32.1 (9/28)
Tumor size > 5 cm	31	66.7 (8/12)	25.0 (3/12)
< 5 cm	12	64.5 (20/31)	32.3 (10/31)
Intrahepatic metastasisb Yes	15	86.7 (13/15)	40.0 (6/15)
No	28	46.4 (13/28)	25.0 (7/28)

^aP < 0.01;

^bP < 0.05