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©The Author(s) 2000.
World J Gastroenterol. Jun 15, 2000; 6(3): 402-404
Published online Jun 15, 2000. doi: 10.3748/wjg.v6.i3.402
Published online Jun 15, 2000. doi: 10.3748/wjg.v6.i3.402
Table 1 Effects of SA-A on ALT, AST and LDH activities in hepatocytes injured for 24 h (n = 6, -x±s)
Group | ALT (U·L-1) | AST (U·L-1) | LDH (U·L-1) |
Normal | 18 ± 2.8b | 56 ± 3.8b | 77 ± 38b |
Control | 103 ± 6.5 | 176 ± 9.1 | 1674 ± 128 |
10-4 mol·L-1 SA-A | 49 ± 2.9bd | 134 ± 5.0bd | 1050 ± 83bd |
10-5 mol/L SA-A | 72 ± 3.9bd | 177 ± 8.3 | 1551 ± 88 |
10-6 mol/L SA-A | 91 ± 11.1a | 177 ± 9.2 | 1602 ± 88 |
10-7 mol/L SA-A | 96 ± 7.9 | 181 ± 6.7 | 1657 ± 81 |
10-8 mol/L SA-A | 93 ± 11.4 | 181 ± 10.7 | 1684 ± 71 |
Vitamin E | 86 ± 7.6b | 182 ± 10.7 | 1509 ± 30a |
Table 2 Effects of SA-A on the contents of MDA and GSH and the activities of SOD, CAT and GSH-PX in hepatocytes injured by peroxidation (n = 6, -x±s)
Group | MDA (μmol·L-1) | SOD (U·L-1) | CAT (U·L-1) | GSH (U·L-1) | GSH-PX (U·L-1) |
Normal | 5.11 ± 0.91b | 30.4 ± 2.86b | 12.8 ± 3.45b | 1.27 ± 0.13b | 16.7 ± 8.84b |
Control | 9.17 ± 0.80 | 59.0 ± 2.23 | 86.6 ± 13.00 | 0.36 ± 0.07 | 90.9 ± 11.00 |
10-3 mol/L SA-A | 6.79 ± 0.81a | 45.6 ± 3.26bd | 17.3 ± 3.59bd | 0.95 ± 0.02bd | 65.2 ± 1.24a |
10-4 mol/L SA-A | 7.67 ± 1.11 | 55.2 ± 2.44 | 38.3 ± 11.82b | 0.40 ± 0.04 | 81.8 ± 17.54 |
10-5 mol/L SA-A | 8.27 ± 1.50 | 57.6 ± 3.27 | 49.9 ± 6.78b | 0.38 ± 0.10 | 84.1 ± 19.11 |
Vitamin E | 7.52 ± 0.69a | 55.8 ± 4.03 | 27.6 ± 3.22b | 0.49 ± 0.07a | 63.64 ± 10.57a |
- Citation: Hu YY, Liu CH, Wang RP, Liu C, Zhu DY, Liu P. Protective actions of salvianolic acid A on hepatocyte injured by peroxidation in vitro. World J Gastroenterol 2000; 6(3): 402-404
- URL: https://www.wjgnet.com/1007-9327/full/v6/i3/402.htm
- DOI: https://dx.doi.org/10.3748/wjg.v6.i3.402