Effects of Dangshen on isolated gastric muscle strips in rats

Table 1 Effect of Dangshen and antagonists plus Dangshen on the resting tension of the fundus in rats

	1%	3%	10%	30%	100%	200%
Dangshen	0	5.4 ± 3.3	38.8 ± 6.9b	75.8 ± 11.9b	153.8 ± 17.9b	163.3 ± 20.0b
	(n = 12)	(n = 12)	(n = 12)	(n = 12)	(n = 12)	(n = 12)
Atropine (5 × 10-8 mol/L) + Dangshen	1.0 ± 0.7	4.3 ± 2.2	18.0 ± 4.8bc	38.0 ± 10.5bc	120.3 ± 21.9b	132.3 ± 23.0b
	(n = 15)	(n = 15)	(n = 15)	(n = 15)	(n = 15)	(n = 15)
Hexamethonium(10-5 mol) + Dangshen	-1.8 ± 1.3	-1.5 ± 1.8	14.1 ± 5.7ad	42.6 ± 9.3bc	143.0 ± 21.7b	179.4 ± 28.8b
	(n = 17)	(n = 17)	(n = 17)	(n = 17)	(n = 17)	(n = 17)
Indomethacin(5 × 10-7 mol/L) + Dangshen	0	0	14.3 ± 5.4ac	42.1 ± 14.9a	116.4 ± 24.1b	157.8 ± 29.9b
	(n = 14)	(n = 14)	(n = 14)	(n = 14)	(n = 14)	(n = 14)

^aP < 0.05,

^bP < 0.01 vs control;

^cP < 0.05,

^dP < 0.01 vs Dangshen on the same concentration; 0, no effect; ^-x±s_x (%) increase.