Triglyceride-glucose index as a prognostic indicator in advanced gastric cancer: Insights and future research

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May 7, 2025 (publication date) through Apr 29, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 7, 2025; 31(17): 104794
Published online May 7, 2025. doi: 10.3748/wjg.v31.i17.104794

Table 1 Triglyceride-glucose index in combination with three other biomarkers[22-24]

Biomarker	Role in tumor immunity	Complementary role in combination with TyG	Ref.
TyG	Reflecting metabolism-immune interaction
TMB	Reflecting tumor antigen load	Predicting the sensitivity to immunotherapy	Cristescu et al[22]
PD-L1	Reflecting immune checkpoint status	Guiding the selection of immunotherapy	Le et al[23]
ctDNA	Reflecting real-time monitoring of tumor load	Dynamic assessment of treatment response	Tie et al[24]

TyG: Triglyceride-glucose; TMB: Tumor mutational burden; PD-L1: Programmed cell death ligand 1; ctDNA: Circulating tumor DNA.

Citation: Zhao CF, Liu XL, Wu NB, Xu ZF. Triglyceride-glucose index as a prognostic indicator in advanced gastric cancer: Insights and future research. World J Gastroenterol 2025; 31(17): 104794
URL: https://www.wjgnet.com/1007-9327/full/v31/i17/104794.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i17.104794