Retrospective Study
Copyright ©The Author(s) 2024.
World J Gastroenterol. Feb 21, 2024; 30(7): 673-684
Published online Feb 21, 2024. doi: 10.3748/wjg.v30.i7.673
Table 1 Demographic information, lesion characteristics, and procedural outcomes of early gastric cancer, n (%)
        
GCP (n = 104)
Demographic information
        Male77 (74.0)
        Age (yr), mean ± SD63.4 ± 11.0
        History of gastric endoscopic or surgical treatment13 (12.5)
Symptom
        Asymptomatic66 (63.5)
        Epigastric discomfort28 (26.9)
        Regurgitation8 (7.7)
        Melena2 (1.9)
Lesion characteristics
Growth pattern
        Intraluminal growth103 (99.0)
        Extraluminal growth1 (1.0)
Morphology
        Regular77 (74.0)
        Irregular27 (26.0)
Mucosa
        Smooth40 (38.5)
        Ulcerative64 (61.5)
        Max diameter (mm), mean ± SD20.9 ± 15.3
Location
        Cardia40 (38.5)
        Gastric fundus8 (7.7)
        Gastric body35 (33.7)
        Gastric antrum21 (20.2)
Endoscopic features
        Mucosal lesion type62 (59.6)
            IIa29 (46.8)
            IIa + IIc4 (6.5)
            IIc29 (46.8)
        Polypoid type23 (22.1)
        Submucosal lesion type17 (16.3)
        Thickened mucosa with rough wrinkles type2 (1.9)
Infiltration depth
        Mucosa63 (60.6)
        Submucosa40 (38.5)
        Muscularis propria1 (1.0)
        GCP with EGC62 (59.6)
Procedural outcomes
Endoscopic methods
        Electric cutting7 (6.7)
        EMR11 (10.6)
        ESD80 (76.9)
        ESE6 (5.8)
        En-bloc resection95 (91.3)
        Complete resection95 (91.3)
Suture method
        Unstitched62 (59.6)
        Metal clip40 (38.5)
        Nylon rope1 (1.0)
        Metal clip and nylon rope1 (1.0)
        Surgery time (min), mean ± SD73.9 ± 57.5
        Complications1 (1.0)
        Hospital stay (d), mean ± SD3.4 ± 2.3
        Additional surgery1 (1.0)
        Recurrence5 (4.8)
Table 2 Demographic information, lesion characteristics, and procedural outcomes of the early gastric cancer without early gastric cancer s and early gastric cancer with early gastric cancer s groups, n (%)
        
GCP without EGCs (n = 42)
GCP with EGCs (n = 62)
P value
Demographic information
        Male23 (54.8)54 (87.1)< 0.001
        Age (yr), mean ± SD58.5 ± 11.966.7 ± 9.1< 0.001
        History of gastric endoscopic or surgical treatment4 (9.5)9 (14.5)0.450
Symptom0.158
        Asymptomatic23 (54.8)43 (69.4)
        Epigastric discomfort15 (35.7)13 (21.0)
        Regurgitation4 (9.5)4 (6.5)
        Melena0 (0)2 (3.2)
Lesion characteristics
Growth pattern1.000
        Intraluminal growth42 (100)61 (98.4)
        Extraluminal growth0 (0)1 (1.6)
Morphology0.007
        Regular37 (88.1)40 (64.5)
        Irregular5 (11.9)22 (35.5)
Mucosa< 0.001
        Smooth27 (64.3)13 (21.0)
        Ulcerative15 (35.7)49 (79.0)
        Max diameter (mm), mean ± SD18.0 ± 14.422.9 ± 15.70.110
Location0.003
        Cardia9 (21.4)31 (50.0)
        Gastric fundus7 (16.7)1 (1.6)
        Gastric body16 (38.1)19 (30.6)
        Gastric antrum10 (23.8)11 (17.7)
Endoscopic features< 0.001
        Mucosal lesion type8 (19.0)54 (87.1)
            IIa6 (75.0)23 (42.6)
            IIa + IIc0 (0)4 (7.4)
            IIc2 (25.0)27 (50.0)
        Polypoid type19 (45.2)4 (6.5)
        Submucosal lesion type13 (31.0)4 (6.5)
        Thickened mucosa with rough wrinkles type2 (4.8)0 (0)
Infiltration depth0.363
        Mucosa24 (57.1)39 (62.9)
        Submucosa17 (40.5)23 (37.1)
        Muscularis propria1 (2.4)0 (0)
Procedural outcomes
Endoscopic methods< 0.001
        Electric cutting7 (16.7)0 (0)
        EMR11 (26.2)0 (0)
        ESD18 (42.9)62 (100)
        ESE6 (14.3)0 (0)
        En-bloc resection38 (90.5)57 (91.9)1.000
        Complete resection38 (90.5)57 (91.9)1.000
Suture method0.011
        Unstitched18 (42.9)44 (71)
        Metal clip23 (54.8)17 (27.4)
        Nylon rope1 (2.4)0 (0)
        Metal clip and nylon rope0 (0)1 (1.6)
        Surgery time (min), mean ± SD38.5 ± 38.696.6 ± 56.3< 0.001
        Complications1 (2.4)0 (0)0.404
        Hospital stay (d), mean ± SD2.6 ± 1.83.9 ± 2.50.006
        Additional surgery0 (0)1 (1.6)1.000
        Recurrence2 (4.8)3 (4.8)1.000
Table 3 Multivariate logistic regression analysis for gastric cystica profunda with early gastric cancers
FactorsMultivariate analysis
OR [95%CI]
β coefficient
P value
Location
        Cardia1
        Non-cardia0.881 [0.226-3.424]-0.1260.853
Sex
        Male3.323 [0.771-14.764]1.2010.104
        Female1
Morphology
        Regular1
        Irregular15.278 [2.965-111.712]2.7260.003
Endoscopic features
        Mucosal lesion type1
        Non-mucosal lesion type0.029 [0.006-0.108]-3.531< 0.001
        Age1.026 [0.968-1.090]0.0250.392