Macrophage-derived cathepsin L promotes epithelial-mesenchymal transition and M2 polarization in gastric cancer

Table 1 Demographic data of the patients enrolled in our study, n (%)

Characteristic	Overall (n = 91)	PM (-) (n = 64)	PM (+) (n = 27)	P value1
Sex				0.479
Female	20.00 (25.97)	16.00 (28.07)	4.00 (20.00)
Male	57.00 (74.03)	41.00 (71.93)	16.00 (80.00)
Unknown	14	7	7
Patient age, median (interquartile range)	63.00 (56.00–69.00)	64.00 (58.00–71.00)	62.00 (52.00–66.00)	0.121
Unknown	14	7	7
T stage				0.304
1	5.00 (6.49)	5.00 (8.77)	0.00 (0.00)
2	5.00 (6.49)	5.00 (8.77)	0.00 (0.00)
3	13.00 (16.88)	10.00 (17.54)	3.00 (15.00)
4	54.00 (70.13)	37.00 (64.91)	17.00 (85.00)
Unknown	14	7	7
N stage				< 0.001
x	7.00 (9.09)	0.00 (0.00)	7.00 (35.00)
0	18.00 (23.38)	16.00 (28.07)	2.00 (10.00)
1	13.00 (16.88)	12.00 (21.05)	1.00 (5.00)
2	13.00 (16.88)	11.00 (19.30)	2.00 (10.00)
3	26.00 (33.77)	18.00 (31.58)	8.00 (40.00)
Unknown	14	7	7
M stage				< 0.001
0	57.00 (74.03)	57.00 (100.00)	0.00 (0.00)
1	20.00 (25.97)	0.00 (0.00)	20.00 (100.00)
Unknown	14	7	7
Stage				< 0.001
I	6.00 (7.79)	6.00 (10.53)	0.00 (0.00)
II	17.00 (22.08)	17.00 (29.82)	0.00 (0.00)
III	34.00 (44.16)	34.00 (59.65)	0.00 (0.00)
IV	20.00 (25.97)	0.00 (0.00)	20.00 (100.00)
Unknown	14	7	7

¹Pearson's χ²; Wilcoxon rank sum test; Fisher's exact test.