Advancing prognostic precision in gastric cancer with an immunoinflammatory index

Table 1 Calculation rules for prognostic immunoinflammatory index and other indices

Index	Calculation rule
PLR	Platelet count/lymphocyte count
LMR	Lymphocyte count/monocyte count
PNI	Albumin + 5 × lymphocyte count
NLR	Neutrophil count/lymphocyte count
SII	Neutrophil count/lymphocyte count × platelet count
SIRI	Neutrophil count × monocyte count/lymphocyte count
SII-PNI	High SII (≥ 471.5) and low PNI (≤ 48.6) were scored as 1, and the rest of the values were scored as 0
INPS	Low BMI (< 23 kg/m2), low prealbumin (< 180 mg/L), high NLR (≥ 2.7), high PLR (≥ 209.4), low LMR (< 2.8), and low PNI (< 45.1) were scored as 1, and the rest of the values were scored as 0
PII	0.608 × NLR + 0.277 × PLR + 0.059 × SIRI + 0.480 × CD3(+) + 0.176 × CD3(+)CD16(+)CD56(+) - 0.459 × CD4(+)CD8(+) - 0.501 × CD19(+)

PLR: Platelet-to-lymphocyte ratio; LMR: Lymphocyte-to-monocyte ratio; PNI: Prognostic nutritional index; NLR: Neutrophil-to-lymphocyte ratio; SII: Systemic immune-inflammatory index; SIRI: Systemic inflammation response index; INPS: Inflammation, nutritional status, and clinicopathological parameters; BMI: Body mass index; PII: Prognostic immunoinflammatory index.