Retrospective Study
Copyright ©The Author(s) 2024.
World J Gastroenterol. Nov 21, 2024; 30(43): 4609-4619
Published online Nov 21, 2024. doi: 10.3748/wjg.v30.i43.4609
Table 1 Clinical characteristics of 210 patients with esophageal cancer
Clinicopathological data
n
SHOX2 methylation
Septin9 methylation
EPO methylation
RNF180 methylation
Combined methylation detection
Tumor pathology
Adenocarcinoma 33
Squamous cell carcinoma177
P value0.3540.190.5240.0980.527
Gender
Male122
Female88
Male vs female0.4160.3790.4390.2790.464
Age at diagnosis
≤ 60 years73
> 60 years137
Median age (years)65.6
Mean age (years)63.5
≤ 60 vs > 60 years 0.6650.0110.0210.2110.001
Tumor stage
I-II19
III-IV191
I-II vs III-IV0.0190.0220.0010.1490.001
Follow-up
Follow-up available23
Table 2 Results of logistic regression analysis (Cox proportional hazard models)
Univariate analysis

Number of patients
OR (95%CI)
P value
Gender(Male vs female)2100.65 (0.32-1.34)0.568
Age at diagnosis(≤ 60 vs > 60 years)2102.32 (1.45-6.61) 0.021
SCCA(≤ 3.5 vs > 3.5 U/mL)2103.01 (1.54-6.45)0.023
EPO methylation(EPOvs EPO+) 2107.89 (3.28-18.21)0.001
SEPT9
methylation
(SEPT9vs SEPT9+) 2107.15 (2.86-17.63)0.001