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©The Author(s) 2024.
World J Gastroenterol. Jun 21, 2024; 30(23): 2947-2953
Published online Jun 21, 2024. doi: 10.3748/wjg.v30.i23.2947
Published online Jun 21, 2024. doi: 10.3748/wjg.v30.i23.2947
Ref. | n | Treatment | Follow-up GER assessment method | Results and conclusion |
Inoue et al[26], 2019 | 21 | POEM + F | Not assessed | Technical success: 100%. Maintaining wrap at 2 mo: 95%. AE: 0% |
Shrigiriwar et al[33], 2023 | 6 | POEM + F + PPI | GERD-HRQL; RSI | Technical success: 100%. AE: 0%. GERD-HRQL score: 2.3 ± 3.7. RSI Score: 2.2 ± 2.5 |
Patil et al[35], 2021 | 20 | POEM + F + PPI | 24 h pHmetry; endoscopy | Technical success: 85%. Subcutaneous emphysema: 47%. Capnothorax: 17%. At 1 mo follow-up grade B esophagitis: 23.5%. At 3 mo pHmetry: High AET in those with loosening of wrap 100%. At 3 mo pHmetry: Normal AET in those who maintained wrap 100%. Maintaining wrap at 3 mo: 58.8%. Patient off PPI after 3 mo: 58.8% |
Toshimori et al[36], 2020 | 1 | POEF for refractory GERD with erosive esophagitis after POEM | Endoscopy | Technical success without notable AE with maintaining the wrap at a 10-mo follow-up endoscopy. Improved symptoms. No erosive esophagitis |
Maydeo et al[37], 2023 | 30 | EFTP | GERDQ; endoscopy. 24 pHmetry | Maintaining flap at 3 mo: 89.6%. AE: 13.8% “mild symptoms”. Symptoms resolution and PPI stoppage after 6 mo: 72.4%. Improvement (> 50% from baseline) in AET: 96.6%. GERDQ improvement by > 50% at 6 mo: 55.2% |
Bapaye et al[32], 2021 | 25 | POEM + F | GERDQ; endoscopy; 24 pHmetry | Technical success: 92%. Maintaining wrap at 12 mo: 82.6%. AE: 12%. Abnormal AET at 2 mo: 11.1%. Erosive esophagitis at 2 mo: 18.2% |
Ayoub et al[38], 2024 | 4 | TIF + PPI | GERD-HRQL | 75% of patients achieved either dose reduction or discontinuation of PPI. Pre-TIF GERD-HRQL: 20 ± 18.5. Post-TIF GERD-HRQL: 3.75 ± 6.2 |
Hoerter et al[39], 2022 | 1 | TIF | Endoscopy | Technical success without notable AE. Absence of esophagitis at a 9-mo follow-up endoscopy |
Kumta et al[40], 2015 | 1 | TIF | Not assessed | Technical success without notable AE |
DeWitt et al[41], 2024 | 17 | TIF, cTIF | GERD-HRQL; endoscopy; 24 pHmetry | At 9 mo follow-up: Stopped PPI: 80%. Pre-TIF esophagitis: 88%. Post-TIF esophagitis: 50%. Pre-TIF total time reflux episode: 90.5 ± 46.9. Post-TIF total time reflux episode: 49.3 ± 32.3 |
Tyberg et al[25], 2018 | 5 | PPI + TIF | Endoscopy | Technical success: 100%. Complete resolution of symptoms: 100% |
Shiwaku et al[15], 2022 | 1886 | PPI | Endoscopy | Complete resolution of symptoms: 100% at 5-yr follow up |
Nabi et al[42], 2020 | 167 | PPI | Endoscopy | Complete resolution of esophagitis: 81.4% |
Brewer Gutierrez et al[43], 2020 | 67 | PPI | Endoscopy; pHmetry | At 48 mo follow-up erosive esophagitis: 16%. 47.5 % had AET despite being on PPI |
- Citation: Tawheed A, Bahcecioglu IH, Yalniz M, El-Kassas M. Gastroesophageal reflux after per-oral endoscopic myotomy: Management literature. World J Gastroenterol 2024; 30(23): 2947-2953
- URL: https://www.wjgnet.com/1007-9327/full/v30/i23/2947.htm
- DOI: https://dx.doi.org/10.3748/wjg.v30.i23.2947