Histopathology and immunohistochemistry of large hepatocellular carcinoma with undetectable or low serum levels of alpha-fetoprotein

Table 1 Degree of cell differentiation of hepatocarcinomatous tissues

Serum alpha-fetoprotein level (µg/L)	Cases	Degree of differentiation
		I	II	III	IV
≤ 20	18	1	9	7	1
21-299	12	0	9	3	0
Total	30	1	18	10	1

Table 2 Cytomorphological types of hepatocarcinomatous tissue

Serum alpha-fetoprotein level (µg/L)	Number of cases	Morphological types
		Trabecular compact	Clear cell	Giant cell	Spindle cell
≤ 20	18	6	10	1	1
21-299	12	3	9	0	0
Total	30	9	19	1	1

Table 3 Immunohistochemical reactions of hepatocarcinoma

Serum alpha-fetoprotein level (µg/L)	Number of cases	Morphological types
		Trabecular compact	Clear cell	Giant cell	Spindle cell
≤ 20	18	6	10	1	1
21-299	12	3	9	0	0
Total	30	9	19	1	1