Evaluation of a fecal occult blood test with reverse passive hemagglutination for colorectal neoplasm screening

doi:10.3748/wjg.v3.i1.38

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Mar 15, 1997 (publication date) through Mar 7, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 15, 1997; 3(1): 38-40
Published online Mar 15, 1997. doi: 10.3748/wjg.v3.i1.38

Table 1 Relationship between the 1^st reverse passive hemagglutination fecal occult blood test and colorectal neoplasm

		Colorectal neoplasm		Total
		+	-
RPHA FOBT	+	60	250	Total	310
RPHA FOBT	-	380	1863	2243
Total		440	2113	2553

Sensitivity: 13.6% (60/440), specificity: 88.2% (1863/2113), positive predictive value: 16.1% (60/310), negative predictive value: 83.1% (1863/2243).

Table 2 Relationship between the 2^nd reverse passive hemagglutination fecal occult blood test and colorectal neoplasm

		Colorectal neoplasm		Total
		+	-
RPHA FOBT	+	50	168	Total	236
RPHA FOBT	-	372	1823	2195
Total		422	2009	2431

Sensitivity: 11.8% (50/422), specificity: 90.7% (1823/2009), positive predictive value: 21.2% (50/236), negative predictive value: 83.1% (1823/2195).

Table 3 Relationship between the 3^rd reverse passive hemagglutination fecal occult blood test and colorectal neoplasm

		Colorectal neoplasm		Total
		+	-
RPHA FOBT	+	55	151	Total	206
RPHA FOBT	-	333	1733	2066
Total		388	1884	2272

Sensitivity: 14.2% (55/388), specificity: 92.0% (1733/1884), positive predictive value: 26.7% (55/206), negative predictive value: 83.9% (1773/2066).

Table 4 Relationship between three sampling 1/3 (+) and colorectal neoplasm

		Colorectal neoplasm		Total
		+	-
RPHA FOBT	+	85	346	Total	431
RPHA FOBT	-	302	1539	1841
Total		387	1885	2272

Sensitivity: 22.0% (85/387), specificity: 81.6% (1539/1885), positive predictive value: 19.7% (85/431), negative predictive value: 83.6% (1539/1841).

Table 5 Relationship between three sampling 2/3 (+) and colorectal neoplasm

		Colorectal neoplasm		Total
		+	-
RPHA FOBT	+	46	138	Total	184
RPHA FOBT	-	341	1747	2088
Total		387	1885	2272

Sensitivity: 11.9% (46/341), specificity: 92.7% (1747/1885), positive predictive value: 25.0% (46/184), negative predictive value: 83.7% (1747/2088).

Table 6 Relationship between three sampling 3/3 (+) and colorectal neoplasm

		Colorectal neoplasm		Total
		+	-
RPHA FOBT	+	21	66	Total	87
RPHA FOBT	-	366	1819	2185
Total		387	1885	2272

Sensitivity: 5.4% (21/387), specificity: 96.5% (1819/1885), positive predictive value: 24.1% (21/87), negative predictive value: 83.2% (1819/2185)

Citation: Zhou L, Yu H, Zheng S. Evaluation of a fecal occult blood test with reverse passive hemagglutination for colorectal neoplasm screening. World J Gastroenterol 1997; 3(1): 38-40
URL: https://www.wjgnet.com/1007-9327/full/v3/i1/38.htm
DOI: https://dx.doi.org/10.3748/wjg.v3.i1.38