Intestinal barrier in inflammatory bowel disease: A bibliometric and knowledge-map analysis

Table 1 The top 10 countries/regions and institutions in the intestinal barrier field relevant to inflammatory bowel disease

Country	Centrality	Count	Citation	CPR	Institution	Centrality	Count	Citation	CPR
United States	0.30	1534	90667	59.1	University of Chicago	0.08	87	8288	95.3
China	0.26	1383	25867	18.7	University of Calgary	0.06	84	4051	48.2
Germany	0.18	533	37129	69.7	Emory University	0.09	83	6183	74.5
Canada	0.09	352	17335	49.2	Shanghai Jiao Tong University	0.07	74	2323	31.4
United Kingdom	0.28	336	23096	68.7	University of Toronto	0.05	68	3125	46.0
Italy	0.12	266	12121	45.6	Harvard Medical School	0.07	62	1883	30.4
Japan	0.10	244	8467	34.7	Chinese Academy of Sciences	0.04	62	1600	25.8
France	0.16	226	11080	49.0	University of California San Diego	0.07	59	6034	102.3
Sweden	0.02	178	11089	62.3	University of Alberta	0.06	58	3310	57.1
Netherlands	0.03	168	7693	45.8	McMaster University	0.05	58	4047	69.8

CPR: Citations per publication.

Table 2 The top 10 productive authors and cited authors in the intestinal barrier field relevant to inflammatory bowel disease

Ref.	Count	H-index	Ref.	Count	H-index
Turner[18]	35	78	Turner[18]	3399	78
Söderholm et al[19-21]	32	46	Neurath[35]	3257	87
Keshavarzian et al[22-25]	28	77	Ma et al[40]	2811	26
Rogler[59]	26	66	Hansson[60]	2785	71
Neurath[35]	25	87	Johansson et al[61]	2725	47
Schulzke et al[62]	23	58	Al-Sadi et al[63]	2489	21
Merlin et al[64]	23	62	Danese and Fiocchi[46]	2440	96
Ma et al[40]	22	26	Becker et al[44]	2319	61
Fromm et al[34]	21	66	Schulzke et al[62]	1852	58
Vermeire et al[51]	21	122	Nusrat et al[33]	1838	47

Table 3 The top 10 journals and co-cited journals in the intestinal barrier field relevant to inflammatory bowel disease

Journal	Count	IF (2022)	JCR (2022)	Cited journal	Citation	IF (2022)	JCR (2022)
Inflammatory Bowel Diseases	258	7.290	Q1	Gastroenterology	14345	33.883	Q1
PLos One	145	3.752	Q2	Gut	12840	31.793	Q1
American Journal of Physiology-Gastrointestinal and Liver Physiology	119	4.871	Q1/Q2	Inflammatory Bowel Diseases	10188	69.504	Q1
Gastroenterology	118	33.883	Q1	American Journal of Physiology-Gastrointestinal and Liver Physiology	8962	4.871	Q1/Q2
World Journal of Gastroenterology	107	5.374	Q2	Plos One	6557	3.752	Q2
Gut	94	31.793	Q1	Proceedings of the National Academy of Sciences of the United States of America	6250	12.779	Q1
Frontiers in Immunology	86	8.786	Q1	Nature	4978	69.504	Q1
Food & Function	83	6.317	Q1	World Journal of Gastroenterology	4509	5.374	Q2
Digestive Diseases and Sciences	78	3.487	Q3	Journal of Immunology	4142	5.426	Q2
Scientific Reports	74	4.996	Q2	Journal of Clinical Investigation	3390	19.456	Q1

IF: Impact factor; JCR: Journal Citation Reports.

Table 4 The top 10 molecules, pathological processes and disease in the intestinal barrier field relevant to inflammatory bowel disease

Molecule	Count	Pathological process	Count	Treatment	Count
NF-kB	418	Apoptosis	292	Probiotic	237
TNF-α	329	Oxidative stress	232	Nanoparticles	77
IFN-gamma	173	Metabolism	88	Antioxidant	73
Mucin	100	Dysbiosis	83	Butyrate	70
Occludin	90	Autophagy	82	Infliximab	66
Nitric oxide	87	Infection	80	Polysaccharide	48
ZO-1	55	Bacterial translocation	68	Prebiotic	40
Claudin-2	54	Endoplasmic reticulum stress	65	Fecal microbiota transplantation	37
E-cadherin	51	Transport	59	Lactobacillus	32
Antimicrobial peptide	50	Absorption	50	Vitamin D	26

NF-kB: Nuclear factor kappa B; TNF-α: Tumor necrosis factor-α; IFN: Interferon.