Prolonged hyperthermic intraperitoneal chemotherapy duration with 90 minutes cisplatin might increase overall survival in gastric cancer patients with peritoneal metastases

Table 1 P values of the multivariate survival model

Parameter	DSS	OS	RFS
HIPEC duration [60 min (ref.) vs 90 min]	0.0781	0.1541	0.5578
Age (yr)	0.1870	0.1331	0.3691
Sex [male vs female (ref.)]	0.3327	0.2943	0.8681
Stage T [1-2 (ref.) vs 3-4]	0.1205	0.1857	0.0475
Stage N [0 (ref.) vs 1-3]	0.5071	0.4511	0.0902
Histology
ACD (ref.) vs ACI	0.3092	0.2335	0.2471
ACD (ref.) vs SRC	0.9456	0.8638	0.2227
Body-mass index (kg/m2)	0.6394	0.8365	0.3049
Peritoneal carcinomatosis index	0.0569	0.2530	0.2752
White blood cell count (109/L)	0.1843	0.2387	0.0327
Hemoglobin (g/dL)	0.2783	0.2924	0.7656
Carcinoembryonic antigen (ng/mL)	0.0007	0.0005	0.1089

ACD: Diffuse type adenocarcinoma; ACI: Intestinal type adenocarcinoma; DSS: Disease-specific survival; ref.: Reference category; RFS: Recurrence-free survival; OS: Overall survival; SRC: Signet-ring cell adenocarcinoma.