Current and future perspectives on acute-on-chronic liver failure: Challenges of transplantation, machine perfusion, and beyond

Table 1 European Association for the Study of the Liver Chronic Liver Failure Consortium acute-on-chronic liver failure grades

ACLF grades	Number of organ failures
1	Single organ kidney failure
	Single liver, coagulation, circulatory or lung failure with creatine levels ranging from 1.5 mg/dL to 1.9 mg/dL or encephalopathy grade 1 or 2, or both
	Single brain failure with creatinine ranging from 1.5 mg/dL to 1.9 mg/dL
2	2 organ failures
3	3 or more organ failures

ACLF: Acute-on-chronic liver failure.