Assessment of physical stress during the perioperative period of endoscopic submucosal dissection

Table 1 Perioperative changes in resting energy expenditure, resting energy expenditure/basal energy expenditure, and stress factors by endoscopic submucosal dissection

	ESD preoperative state	ESD postoperative state
Gastric cancer
REE (kcal)	1170.3 ± 209.0	1238.4 ± 235.5c
REE/BEE	0.96 ± 0.11	1.03 ± 0.14c
Stress factor		1.07
Colorectal cancer
REE (kcal)	1107.0 ± 204.4	1139.9 ± 185.2c
REE/BEE	0.96 ± 0.12	1.00 ± 0.13c
Stress factor		1.06

^cP < 0.001 vs endoscopic submucosal dissection (ESD) preoperative state.

Data are presented as mean ± SD. The stress factor on ESD in the postoperative state was computed by setting the stress factor on the day of ESD to be 1.0. ESD: Endoscopic submucosal dissection; REE: Resting energy expenditure; BEE: Basal energy expenditure.

Table 2 Endoscopic submucosal dissection perioperative changes in serum opsonic activity measured by lucigenin- and luminol-dependent chemiluminescence

	The day of ESD	POD1	POD4
Gastric cancer
Lucigenin
Peak height (%)	100.6	106.3b	105.9b
	(71.4-178.5)	(78.5-282.4)	(77.6-214.4)
Area under the curve (%)	98.4	105.6b	103.5b
	(48.7-184.7)	(64.8-265.3)	(66.0-222.8)
Luminol
Peak height (%)	98.4	100.1	99.6
	(62.7-168.3)	(63.6-199.2)	(69.7-186.6)
Area under the curve (%)	99.7	102.6	101.8
	(68.2-155.7)	(68.0-182.9)	(73.2-170.7)
Colorectal cancer
Lucigenin
Peak height (%)	102.3	105.2	105.3a
	(71.4-132.7)	(61.8-137.4)	(65.7-137.1)
Area under the curve (%)	99.4	101.9	102.6a
	(68.2-134.3)	(60.9-140.0)	(64.0-139.7)
Luminol
Peak height (%)	97.3	100.2	99.9
	(70.9-132.5)	(76.6-132.0)	(74.9-134.7)
Area under the curve (%)	99.1	102.1	102.3
	(75.8-131.4)	(78.3-128.6)	(77.4-134.3)

^aP < 0.05, ^bP < 0.01 vs the day of endoscopic submucosal dissection.

Data are expressed as median with interquartile range in parenthesis. ESD: Endoscopic submucosal dissection; POD: Postoperative day.